Normand B, Maublant J, d'Agrosa M C, Lusson J R, Cassagnes J, Veyre A
Service de Médecine Nucléaire, Centre Jean Perrin, Clermont-Ferrand, France.
Nucl Med Commun. 1991 May;12(5):393-6. doi: 10.1097/00006231-199105000-00003.
The distributions of 201Tl and 99Tcm-MIBI on stress images were quantitatively measured in a series of 15 patients presenting with documented coronary artery disease. Following two sequential, one-week apart, peak-exercise injections of either 74 MBq of 201Tl or 370 MBq of 99Tcm-MIBI, tomographic views of the myocardium were reconstructed and two thick, central short-axis sections were divided into nine sectors. A sector was considered as showing a defect if its relative activity was lower than 30, 40, 50 or 60% of the highest level of activity in the 18 sectors. Results demonstrate that there were more defects with 201Tl than with 99Tcm-MIBI. However, the difference disappeared if the inferior wall was not included. These results suggest that depth attenuation could be, at least partly, responsible for the higher rate of positive results observed in single photon emission computed tomography with 201Tl than with 99Tcm-MIBI.
对一系列15例有记录的冠状动脉疾病患者的应激图像上的201铊和99锝-甲氧基异丁基异腈分布进行了定量测量。在连续两次、间隔一周的运动高峰时分别注射74MBq的201铊或370MBq的99锝-甲氧基异丁基异腈后，重建心肌断层图像，将两个厚的中央短轴切片分为九个节段。如果一个节段的相对活性低于18个节段中最高活性水平的30%、40%、50%或60%，则认为该节段显示有缺损。结果表明，201铊所致的缺损比99锝-甲氧基异丁基异腈更多。然而，如果不包括下壁，则差异消失。这些结果表明，深度衰减可能至少部分是导致在单光子发射计算机断层扫描中观察到的201铊阳性结果率高于99锝-甲氧基异丁基异腈的原因。
