Krasowska Anna
Zakład Biotransformacji, Wydział Biotechnologii, Uniwersytet Wrocławski, 51-148 Wrocław.
Postepy Hig Med Dosw (Online). 2010 Jul 23;64:310-3.
Biosurfactants, amphiphilic compounds, synthesized by microorganisms have surface, antimicrobial and antitumor properties. Biosurfactants prevent adhesion and biofilms formation by bacteria and fungi on various surfaces. For many years microbial surfactants are used as antibiotics with board spectrum of activity against microorganisms. Biosurfactants act as antiviral compounds and their antitumor activities are mediated through induction of apoptosis. This work presents the current state of knowledge related to biomedical activity of biosurfactants.
生物表面活性剂是由微生物合成的两亲化合物,具有表面活性、抗菌和抗肿瘤特性。生物表面活性剂可防止细菌和真菌在各种表面上黏附和形成生物膜。多年来,微生物表面活性剂一直被用作具有广泛抗微生物活性谱的抗生素。生物表面活性剂具有抗病毒化合物的作用,其抗肿瘤活性是通过诱导细胞凋亡来介导的。本文介绍了与生物表面活性剂生物医学活性相关的当前知识状态。