Fjeldstad Cecilie, Pardo Gabriel, Bemben Debra, Bemben Michael
MS Center of Oklahoma, NeuroScience Institute, Oklahoma City 73120, USA.
Int J Rehabil Res. 2011 Mar;34(1):53-8. doi: 10.1097/MRR.0b013e32833d6ccb.
To evaluate balance in women with multiple sclerosis (MS) who have low disability and minimal clinical impairments as measured by the Expanded Disability Status Scale (EDSS), and compare them with healthy age-matched controls. Patients were aged between 18 and 64 years; 67 individuals with MS (μ=44.0 ± 1.2 years) and 45 healthy controls (μ=40.4 ± 2.4 years). All patients had an EDSS score of 3.5 or below. Both the groups underwent a series of balance measures using the NeuroCom Balance Master. The mean EDSS for the MS group was 1.8. For balance, there was a significant difference between the two groups, with the MS group performing worse on the modified clinical test for sensory integration of balance measures standing on a foam surface with eyes closed (P<0.01). A significant difference was also found for the unilateral stance with eyes closed and eyes open, and the tandem walk, with the MS group showing significantly more sway during those tests (P<0.01). The MS group did significantly worse when compared with the healthy age-matched controls on the balance measures, indicating greater postural instability despite the low disability measured by EDSS.
为评估残疾程度较低且根据扩展残疾状态量表（EDSS）测量临床损伤最小的多发性硬化症（MS）女性的平衡能力，并将她们与年龄匹配的健康对照者进行比较。患者年龄在18至64岁之间；67例MS患者（平均年龄44.0±1.2岁）和45例健康对照者（平均年龄40.4±2.4岁）。所有患者的EDSS评分均为3.5或以下。两组均使用NeuroCom Balance Master进行了一系列平衡测试。MS组的平均EDSS为1.8。在平衡方面，两组之间存在显著差异，MS组在闭眼站在泡沫表面的平衡测量感觉整合改良临床测试中表现更差（P<0.01）。在闭眼和睁眼单腿站立以及直线行走测试中也发现了显著差异，MS组在这些测试中表现出明显更多的晃动（P<0.01）。与年龄匹配的健康对照者相比，MS组在平衡测试中的表现明显更差，这表明尽管EDSS测量的残疾程度较低，但姿势不稳定程度更高。
