Thoughtful House Center for Children, Austin, TX, USA.
J Autism Dev Disord. 2011 May;41(5):575-88. doi: 10.1007/s10803-010-1075-y.
Hyperbaric oxygen therapy (HBOT) has been used to treat individuals with autism. However, few studies of its effectiveness have been completed. The current study examined the effects of 40 HBOT sessions at 24% oxygen at 1.3 ATA on 11 topographies of directly observed behavior. Five replications of multiple baselines were completed across a total of 16 participants with autism spectrum disorders. No consistent effects were observed across any group or within any individual participant, demonstrating that HBOT was not an effective treatment for the participants in this study. This study represents the first relatively large-scale controlled study evaluating the effects of HBOT at the level of the individual participant, on a wide array of behaviors.
高压氧治疗（HBOT）已被用于治疗自闭症患者。然而，已经完成的关于其有效性的研究很少。本研究考察了在 1.3ATA 下以 24%氧气进行 40 次 HBOT 对 11 种直接观察行为的影响。共有 16 名自闭症谱系障碍患者完成了总共 5 次多个基线的重复。在任何组或任何单个参与者中都没有观察到一致的效果，这表明 HBOT 对本研究中的参与者不是一种有效的治疗方法。本研究代表了首次在个体参与者层面上，对广泛行为进行的相对大规模的对照评估 HBOT 效果的研究。
