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肢体长度对胃旁路手术患者的重要性——基于证据的综述。

The importance of the length of the limbs for gastric bypass patients--an evidence-based review.

机构信息

Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Carolinas Weight Management and Wellness Center, Carolinas Medical Center, Charlotte, NC 28203, USA.

出版信息

Obes Surg. 2011 Jan;21(1):119-24. doi: 10.1007/s11695-010-0239-3.

Abstract

The ideal length of the gastric bypass limbs is debated. Recent evidence suggests that standard limb lengths used today have a limited impact on patient weight loss. Our objective was to appraise critically the available evidence on the influence of the length of gastric bypass limbs on weight loss outcomes. We systematically reviewed MEDLINE, the Cochrane database of evidence-based reviews, and the Database of Abstracts of Reviews of Effects for articles reporting the effect of gastric bypass length on outcomes published between 1987 and 2009. Four randomized controlled trials and several retrospective studies were identified and reviewed. Longer Roux limb lengths (at least 150 cm) were associated with a very modest weight loss advantage in the short term in superobese patients. No significant impact of alimentary limb length on weight loss for patients with body mass index (BMI) <50 was seen. When the length of the common channel approaches 100 cm, a significant impact on weight loss is observed. The currently available literature supports the notion that a longer Roux limb (at least 150 cm) may be associated with a very modest weight loss advantage in the short term in superobese patients but has no significant impact on patients with BMI ≤50. To achieve weight loss benefit due to malabsorption, bariatric surgeons should focus on the length of the common channel rather than the alimentary or biliopancreatic limbs when constructing a gastric bypass especially in the superobese population where failure rates after conventional gastric bypass are higher.

摘要

胃旁路术的理想吻合口长度仍存在争议。最近的证据表明,目前所使用的标准吻合口长度对患者的减重效果影响有限。本研究旨在对胃旁路术吻合口长度对减重效果影响的相关证据进行系统评价。我们检索了 MEDLINE、Cochrane 系统评价数据库和 Database of Abstracts of Reviews of Effects 数据库,收集了 1987 年至 2009 年间发表的有关胃旁路术吻合口长度对减重效果影响的随机对照研究和回顾性研究。共纳入了 4 项随机对照研究和几项回顾性研究。结果显示,对于超级肥胖患者,吻合口长度较长(至少 150cm)短期内会有轻微的减重优势。而对于 BMI<50 的患者,吻合口长度对减重效果并无显著影响。当共同通道长度接近 100cm 时,其对减重效果的影响才变得显著。目前的文献表明,对于超级肥胖患者,吻合口长度较长(至少 150cm)在短期内可能会有轻微的减重优势,但对于 BMI≤50 的患者并无显著影响。为了获得因吸收不良带来的减重效果,减重外科医生在构建胃旁路术时,应关注共同通道的长度,而不是肠段的长度,尤其是在超级肥胖患者中,传统胃旁路术的失败率更高。

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