快速确定定义tRNA（甘氨酸）受体身份的核苷酸
Rapid determination of nucleotides that define tRNA(Gly) acceptor identity.
作者信息
McClain W H, Foss K, Jenkins R A, Schneider J
机构信息
Department of Bacteriology, University of Wisconsin, Madison 53706-1567.
出版信息
Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6147-51. doi: 10.1073/pnas.88.14.6147.
Abstract
Expression of the genetic code depends on the recognition of specific tRNAs by the enzymes that aminoacylate them. A computer comparison of tRNA sequences coupled with analysis of mutant nonsense-suppressor tRNAs has revealed the structural features that distinguish the acceptor identity of Escherichia coli tRNA(Gly) from tRNAs that accept phenylalanine, arginine, lysine, and glutamine. On replacement of several nucleotides in the acceptor stem and anticodon of the latter tRNAs with tRNA(Gly)-derived residues, the resulting molecules acquired a tRNA(Gly) identity.
摘要
遗传密码的表达取决于使tRNA氨酰化的酶对特定tRNA的识别。tRNA序列的计算机比较以及对突变的无义抑制tRNA的分析揭示了区分大肠杆菌tRNA（Gly）与接受苯丙氨酸、精氨酸、赖氨酸和谷氨酰胺的tRNA的受体身份的结构特征。用tRNA（Gly）衍生的残基替换后一种tRNA的受体茎和反密码子中的几个核苷酸，得到的分子获得了tRNA（Gly）的身份。
相似文献
1
Rapid determination of nucleotides that define tRNA(Gly) acceptor identity.快速确定定义tRNA（甘氨酸）受体身份的核苷酸
Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6147-51. doi: 10.1073/pnas.88.14.6147.
2
Identity of Escherichia coli tRNA(Cys) determined by nucleotides in three regions of tRNA tertiary structure.通过tRNA三级结构三个区域的核苷酸确定大肠杆菌tRNA（Cys）的身份。
J Biol Chem. 1993 Sep 15;268(26):19398-402.
3
Nucleotides that determine Escherichia coli tRNA(Arg) and tRNA(Lys) acceptor identities revealed by analyses of mutant opal and amber suppressor tRNAs.通过对突变的乳白抑制型和琥珀抑制型tRNA的分析揭示的决定大肠杆菌tRNA（精氨酸）和tRNA（赖氨酸）受体特异性的核苷酸
Proc Natl Acad Sci U S A. 1990 Dec;87(23):9260-4. doi: 10.1073/pnas.87.23.9260.
4
Glycyl-tRNA synthetase from Thermus thermophilus--wide structural divergence with other prokaryotic glycyl-tRNA synthetases and functional inter-relation with prokaryotic and eukaryotic glycylation systems.嗜热栖热菌的甘氨酰-tRNA合成酶——与其他原核甘氨酰-tRNA合成酶存在广泛的结构差异以及与原核和真核糖基化系统的功能相互关系。
Eur J Biochem. 1998 Feb 1;251(3):744-57. doi: 10.1046/j.1432-1327.1998.2510744.x.
5
Changing the identity of a tRNA by introducing a G-U wobble pair near the 3' acceptor end.通过在3' 受体末端附近引入一个G-U摆动配对来改变tRNA的身份。
Science. 1988 May 6;240(4853):793-6. doi: 10.1126/science.2452483.
6
Missense and nonsense suppressors can correct frameshift mutations.错义抑制基因和无义抑制基因可以校正移码突变。
Biochimie. 1989 Jun;71(6):729-39. doi: 10.1016/0300-9084(89)90089-8.
7
RNA recognition based on a pair of tertiary hydrogen interaction.基于一对三级氢相互作用的RNA识别。
Nucleic Acids Symp Ser. 1995(33):172-5.
8
Recognition sites of glycine tRNA for glycyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1.嗜热古菌火球菌K1中甘氨酰-tRNA合成酶对甘氨酸tRNA的识别位点。
Nucleic Acids Symp Ser (Oxf). 2005(49):299-300. doi: 10.1093/nass/49.1.299.
9
The crystal structure of a Thermus thermophilus tRNA(Gly) acceptor stem microhelix at 1.6 Å resolution.1.6 Å 分辨率下的嗜热栖热菌 tRNA(Gly)受体茎微环的晶体结构。
Biochem Biophys Res Commun. 2011 Jan 7;404(1):245-9. doi: 10.1016/j.bbrc.2010.11.101. Epub 2010 Nov 27.
10
Recognition of tRNA(Gly) by three widely diverged glycyl-tRNA synthetases.三种差异较大的甘氨酰-tRNA合成酶对tRNA（甘氨酸）的识别
J Mol Biol. 1997 May 9;268(3):640-7. doi: 10.1006/jmbi.1997.0993.
引用本文的文献
1
Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase.质体丙氨酰-tRNA 合成酶两步 tRNA 识别机制的结构基础。
Nucleic Acids Res. 2023 May 8;51(8):4000-4011. doi: 10.1093/nar/gkad144.
2
The tRNA identity landscape for aminoacylation and beyond.tRNA 识别景观：氨酰化及其他功能
Nucleic Acids Res. 2023 Feb 28;51(4):1528-1570. doi: 10.1093/nar/gkad007.
3
Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications.氨酰-tRNA合成酶与tRNA的生物化学及其在无细胞和合成细胞应用中的工程改造
Front Bioeng Biotechnol. 2022 Jul 1;10:918659. doi: 10.3389/fbioe.2022.918659. eCollection 2022.
4
Synthetic Tyrosine tRNA Molecules with Noncanonical Secondary Structures.具有非典型二级结构的合成酪氨酸 tRNA 分子。
Int J Mol Sci. 2018 Dec 26;20(1):92. doi: 10.3390/ijms20010092.
5
X-ray diffraction analysis of a human tRNA(Gly) acceptor-stem microhelix isoacceptor at 1.18 A resolution.人甘氨酸转运核糖核酸（tRNA(Gly)）受体茎微螺旋同功受体在1.18埃分辨率下的X射线衍射分析。
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jan 1;65(Pt 1):59-62. doi: 10.1107/S1744309108040153. Epub 2008 Dec 25.
6
Polynucleotide phosphorylase hinders mRNA degradation upon ribosomal protein S1 overexpression in Escherichia coli.在大肠杆菌中，核糖体蛋白S1过表达时，多核苷酸磷酸化酶会阻碍信使核糖核酸（mRNA）的降解。
RNA. 2008 Nov;14(11):2417-29. doi: 10.1261/rna.1123908. Epub 2008 Sep 29.
7
Human tRNA(Gly) acceptor-stem microhelix: crystallization and preliminary X-ray diffraction analysis at 1.2 A resolution.人tRNA（甘氨酸）受体茎微螺旋：分辨率为1.2埃的晶体学及初步X射线衍射分析
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Oct 1;63(Pt 10):858-61. doi: 10.1107/S1744309107041528. Epub 2007 Sep 19.
8
In silico detection of tRNA sequence features characteristic to aminoacyl-tRNA synthetase class membership.通过计算机模拟检测氨酰-tRNA合成酶类别成员所特有的tRNA序列特征。
Nucleic Acids Res. 2007;35(16):5593-609. doi: 10.1093/nar/gkm598. Epub 2007 Aug 17.
9
Autogenous regulation of Escherichia coli polynucleotide phosphorylase during cold acclimation by transcription termination and antitermination.在冷驯化过程中，大肠杆菌多核苷酸磷酸化酶通过转录终止和抗终止进行自身调节。
Mol Genet Genomics. 2007 Jul;278(1):75-84. doi: 10.1007/s00438-007-0231-3. Epub 2007 Mar 24.
10
Crystallization and preliminary X-ray diffraction analysis of an Escherichia coli tRNA(Gly) acceptor-stem microhelix.大肠杆菌tRNA（甘氨酸）受体茎微螺旋的结晶及初步X射线衍射分析
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jan 1;63(Pt 1):46-8. doi: 10.1107/S1744309106052870. Epub 2006 Dec 22.
本文引用的文献
1
The effect of bisulfite-induced C to U transitions on aminoacylation of Escherichia coli glycine tRNA.亚硫酸氢盐诱导的C到U转换对大肠杆菌甘氨酸tRNA氨酰化的影响。
J Biol Chem. 1982 May 10;257(9):4796-805.
2
Three different missense suppressor mutations affecting the tRNA GGG Gly species of Escherichia coli.影响大肠杆菌tRNA GGG Gly种类的三种不同错义抑制突变。
J Bacteriol. 1974 Feb;117(2):351-9. doi: 10.1128/jb.117.2.351-359.1974.
3
Intrinsic precision of aminoacyl-tRNA synthesis enhanced through parallel systems of ligands.通过配体平行系统提高氨酰-tRNA合成的内在精度。
Nat New Biol. 1972 Sep 27;239(91):106-8. doi: 10.1038/newbio239106a0.
4
Comparison of tRNA sequences.
Comput Appl Biosci. 1987 Mar;3(1):53. doi: 10.1093/bioinformatics/3.1.53.
5
A simple structural feature is a major determinant of the identity of a transfer RNA.一个简单的结构特征是转运RNA身份的主要决定因素。
Nature. 1988 May 12;333(6169):140-5. doi: 10.1038/333140a0.
6
Accuracy of in vivo aminoacylation requires proper balance of tRNA and aminoacyl-tRNA synthetase.体内氨基酰化的准确性需要tRNA和氨基酰-tRNA合成酶的适当平衡。
Science. 1988 Dec 16;242(4885):1548-51. doi: 10.1126/science.3144042.
7
Changing the identity of a transfer RNA.改变转运RNA的身份。
Nature. 1986;321(6067):213-9. doi: 10.1038/321213a0.
8
Anticodon switching changes the identity of methionine and valine transfer RNAs.反密码子转换改变了甲硫氨酸和缬氨酸转运RNA的身份。
Science. 1988 Nov 4;242(4879):765-8. doi: 10.1126/science.3055296.
9
Conditionally lethal and recessive UGA-suppressor mutations in the prfB gene encoding peptide chain release factor 2 of Escherichia coli.大肠杆菌中编码肽链释放因子2的prfB基因的条件致死性和隐性UGA抑制突变。
J Bacteriol. 1988 Nov;170(11):5378-81. doi: 10.1128/jb.170.11.5378-5381.1988.
10
The anticodon contains a major element of the identity of arginine transfer RNAs.反密码子包含精氨酸转运核糖核酸识别的一个主要元件。
Science. 1989 Dec 22;246(4937):1595-7. doi: 10.1126/science.2688091.
Zotero 插件