[黄芪双向固体发酵中黄芪甲苷的转化]
[Transformation of astragaloside IV in bidirectional solid fermenting of Astragalus membranaceus].
作者信息
Ruan Ming, Zhang Li-Yang, Yu Bin, Chen Yu-Sheng, Zhuang Yi
机构信息
Institute of Medicinal Fungi, Department of Life Science, Nanjing Xiaozhuang University, Nanjing 211171, China.
出版信息
Zhong Yao Cai. 2010 Mar;33(3):339-43.
OBJECTIVE
To study the transformation of Astragaloside IV in bidirectional solid fermenting of Astragalus membranaceus var. mongholicus.
METHODS
The chemical components of pre and post-fermenting were comparatively analyzed by techniques of HPLC, column chromatography and spectral identification. Antioxidant effect of transformational product on vascular endothelial cells was researched.
RESULTS
In fermenting of Astragalus membranaceus, Astragaloside IV was transformed into 6-O-beta-D-glucoside cycloastragenol, which had significant antioxidant effect.
CONCLUSION
Biotransformation of Astragaloside IV in Astragalus membranaceus was occurred after bidirectional solid fermenting with Ganoderma lucidum, and the biotransformation could enhance effect.
目的
研究蒙古黄芪双向固体发酵中黄芪甲苷的转化情况。
方法
采用高效液相色谱法、柱色谱法和光谱鉴定技术对发酵前后的化学成分进行比较分析。研究转化产物对血管内皮细胞的抗氧化作用。
结果
在黄芪发酵过程中，黄芪甲苷转化为6-O-β-D-葡萄糖环黄芪醇，具有显著的抗氧化作用。
结论
灵芝对蒙古黄芪进行双向固体发酵后，黄芪甲苷发生了生物转化，且生物转化可增强其作用效果。
Zotero 插件