Centre for the Mind, Main Quadrangle (A14), University of Sydney, NSW 2006, Australia.
Brain Res. 2010 Sep 24;1353:168-75. doi: 10.1016/j.brainres.2010.07.062. Epub 2010 Aug 2.
Our visual memories are susceptible to errors, but less so in people who have a more literal cognitive style. This inspired us to attempt to improve visual memory with non-invasive brain stimulation. We applied 13 min of bilateral transcranial direct current stimulation (tDCS) to the anterior temporal lobes. Our stimulation protocol included 3 conditions, each with 12 neurotypical participants: (i) left cathodal stimulation together with right anodal stimulation, (ii) left anodal stimulation together with right cathodal stimulation, and (iii) sham (control) stimulation. Only participants who received left cathodal stimulation (decrease in excitability) together with right anodal stimulation (increase in excitability) showed an improvement in visual memory. This 110% improvement in visual memory was similar to the advantage people with autism, who are known to be more literal, show over normal people in the identical visual task. Importantly, participants receiving stimulation of the opposite polarity (left anodal together with right cathodal stimulation) failed to show any change in memory performance. This is the first demonstration that visual memory can be enhanced in healthy people using non-invasive brain stimulation.
我们的视觉记忆容易出错,但认知风格更具字面意义的人出错较少。这启发我们尝试通过非侵入性脑刺激来改善视觉记忆。我们对前颞叶施加了 13 分钟的双侧经颅直流电刺激(tDCS)。我们的刺激方案包括 3 种条件,每种条件有 12 名神经典型参与者:(i)左阴极刺激与右阳极刺激相结合,(ii)左阳极刺激与右阴极刺激相结合,以及(iii)假刺激(对照)。只有接受左阴极刺激(兴奋性降低)与右阳极刺激(兴奋性增加)的参与者表现出视觉记忆的改善。这种 110%的视觉记忆改善与自闭症患者的优势相当,众所周知,自闭症患者在相同的视觉任务中比正常人更具字面意义。重要的是,接受相反极性刺激(左阳极与右阴极刺激)的参与者在记忆表现上没有任何变化。这是首次证明使用非侵入性脑刺激可以增强健康人的视觉记忆。
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