大肠杆菌中广泛的反义转录。
Widespread antisense transcription in Escherichia coli.
机构信息
Wadsworth Center, New York State Department of Health, Albany, New York, USA.
出版信息
mBio. 2010 May 18;1(1):e00024-10. doi: 10.1128/mBio.00024-10.
Abstract
The vast majority of annotated transcripts in bacteria are mRNAs. Here we identify ~1,000 antisense transcripts in the model bacterium Escherichia coli. We propose that these transcripts are generated by promiscuous transcription initiation within genes and that many of them regulate expression of the overlapping gene.
摘要
绝大多数细菌的带注释转录本是 mRNA。在这里，我们在模式细菌大肠杆菌中鉴定出了大约 1000 个反义转录本。我们提出这些转录本是由基因内的混杂转录起始产生的，并且其中许多转录本调节重叠基因的表达。
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