Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
J Abnorm Child Psychol. 2011 Jan;39(1):11-9. doi: 10.1007/s10802-010-9449-3.
The nature of executive dysfunction in youth with disruptive behavior disorders (DBD) remains unclear, despite extensive research in samples of children with attention-deficit hyperactivity disorder (ADHD). To determine the relationship between DBD, ADHD, and executive function deficits in aggressive teens, adolescents with DBD and comorbid ADHD (DBD + ADHD; n = 25), DBD without ADHD (DBD-ADHD; n = 23), and healthy controls (HC; n = 25) were compared on neurocognitive tests and questionnaires measuring executive functioning. Teens with DBD + ADHD performed worse on both neurocognitive and questionnaire measures of executive function than the DBD-ADHD and HC groups. Results suggest that subgroups of DBD may exist depending on the presence or absence of comorbid ADHD, which may have implications for the selection and efficacy of treatment strategies.
尽管在患有注意缺陷多动障碍 (ADHD) 的儿童样本中进行了广泛的研究,但具有破坏性行为障碍 (DBD) 的年轻人的执行功能障碍的性质仍不清楚。为了确定 DBD、ADHD 和攻击性青少年的执行功能缺陷之间的关系,将 DBD 伴共患 ADHD (DBD+ADHD; n=25)、无 ADHD 的 DBD (DBD-ADHD; n=23) 和健康对照组 (HC; n=25) 进行比较,评估神经认知测试和测量执行功能的问卷。DBD+ADHD 青少年在神经认知和执行功能问卷测量方面的表现均差于 DBD-ADHD 和 HC 组。结果表明,DBD 可能存在亚组,这取决于是否存在共患 ADHD,这可能对治疗策略的选择和疗效有影响。