Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.
Chem Commun (Camb). 2010 Sep 14;46(34):6282-4. doi: 10.1039/c0cc02013c. Epub 2010 Aug 9.
A new triazolium salt derived N-heterocyclic carbene catalyses an asymmetric cross-benzoin-type reaction of heteroaromatic aldehydes and various trifluoromethyl ketones in good to excellent yields (69-96%) and moderate to good enantioselectivities (ee = 39-85%). Up to 99% ee can be achieved by recrystallisation.
一种新型三唑鎓盐衍生的 N-杂环卡宾催化杂芳醛和各种三氟甲基酮的不对称交叉苯偶姻型反应，产率优异（69-96%），对映选择性适中至良好（ee = 39-85%）。通过重结晶可达到 99%的对映体过量。
