丙型肝炎感染者的延迟奖励折扣和执行功能障碍。
Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis C.
机构信息
Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR 97239, USA.
出版信息
J Clin Exp Neuropsychol. 2011 Feb;33(2):176-86. doi: 10.1080/13803395.2010.499355. Epub 2010 Aug 6.
Abstract
OBJECTIVE
Determine whether adults with hepatitis C (HCV), regardless of substance use disorder, are more likely to discount delayed rewards than adults without hepatitis C, and explore the relationship between delay discounting and neuropsychological functioning.
METHODS
Procedures included clinical interviews, neuropsychological testing, and a delay discounting task.
RESULTS
Regardless of substance abuse history, adults with hepatitis C were significantly more likely to choose smaller immediate rewards over larger delayed rewards. Delay discounting correlated with performance on executive functioning tasks.
CONCLUSIONS
Increased discounting is associated with broad executive dysfunction, suggesting that HCV-associated executive dysfunction may lead to altered decision-making style.
摘要
目的
确定无论是否存在物质使用障碍，患有丙型肝炎（HCV）的成年人是否比没有丙型肝炎的成年人更倾向于低估延迟奖励，以及探讨延迟折扣与神经心理学功能之间的关系。
方法
程序包括临床访谈、神经心理学测试和延迟折扣任务。
结果
无论是否有药物滥用史，患有丙型肝炎的成年人更倾向于选择较小的即时奖励而不是较大的延迟奖励。延迟折扣与执行功能任务的表现相关。
结论
增加的折扣与广泛的执行功能障碍有关，这表明 HCV 相关的执行功能障碍可能导致决策风格的改变。
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