Department of Pediatrics, Division of Pediatric Clinical Research, University of Miami, Miller School of Medicine, Miami, FL 33101, USA.
J Clin Hypertens (Greenwich). 2010 Aug;12(8):645-52. doi: 10.1111/j.1751-7176.2010.00337.x.
This study explored inter- (between) and intra- (within) ethnic group differences in metabolic syndrome components among a clinical sample of morbidly obese (body mass index [BMI] > or =97th percentile for age and sex) 12- to 18-year-olds originating from Latin America and the Caribbean Basin and a matched (age/ethnicity/sex/BMI percentile) national sample (N=208, both samples) of Mexican American and non-Hispanic blacks from the 1999 to 2006 National Health and Nutrition Examination Survey (NHANES). Mexican American and non-Hispanic black boys from the NHANES/national sample had significantly higher mean fasting glucose levels compared with Latin and Caribbean blacks (98.50 vs 85.42 mg/dL, 97.34 vs 86.44 mg/dL, respectively, (P< .001 for both comparisons). Conversely, both diastolic/systolic blood pressure was consistently higher among Latin/Caribbean adolescents vs Mexican American and non-Hispanic blacks for all age/sex/ethnic groups. These results indicate that morbidly obese adolescents from both major ethnic groups and subgroups within these groups show health-related comorbidities in both clinic- and population-based settings.
本研究旨在探讨拉丁美洲和加勒比海地区肥胖青少年(身体质量指数[BMI]≥第 97 百分位数,年龄和性别匹配)临床样本与全国性匹配样本(1999 至 2006 年全国健康和营养调查[NHANES]中,年龄/种族/性别/BMI 百分位数匹配的墨西哥裔美国人和非西班牙裔黑人,n=208)中代谢综合征成分的组间(种族间)和组内(种族内)差异。NHANES/全国性样本中,与墨西哥裔美国人和非西班牙裔黑人相比,肥胖的墨西哥裔美国男孩和非西班牙裔黑人的空腹血糖水平明显更高(分别为 98.50 比 85.42mg/dL 和 97.34 比 86.44mg/dL,P<0.001)。相反,在所有年龄/性别/种族群体中,拉丁/加勒比青少年的舒张压/收缩压均始终高于墨西哥裔美国人和非西班牙裔黑人。这些结果表明,来自这两个主要种族群体及其亚群的肥胖青少年在临床和人群环境中均表现出与健康相关的合并症。