The Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, China.
Anal Chem. 2010 Sep 1;82(17):7380-6. doi: 10.1021/ac101510b.
In this paper, Mn-doped ZnS quantum dots (QDs) capped by a molecularly imprinted polymer (MIP) were synthesized. The results showed a high selectivity of the MIP-capped Mn-doped ZnS QDs toward the template molecule (4-nitrophenol) by QD fluorescence quenching. The application of MIP-capped Mn-doped ZnS QDs to the chemiluminescence (CL) system was also studied using a KIO(4)-H(2)O(2) system. This application combines the good selectivity of MIP with the high sensitivity of CL. The linear range of this CL system is from 0.1 to 40 microM, and the detection limit (DL) for 4-nitrophenol in the water can reach 76 nM. The method was also used in the real water samples, and the recoveries can fall in the range of 91-96%.
本文合成了一种分子印迹聚合物（MIP）包覆的锰掺杂硫化锌量子点（QD）。结果表明，MIP 包覆的 Mn 掺杂 ZnS QD 通过 QD 荧光猝灭对模板分子（4-硝基苯酚）具有高选择性。还研究了 MIP 包覆的 Mn 掺杂 ZnS QD 在 KIO(4)-H(2)O(2)体系中的化学发光（CL）体系中的应用。该应用将 MIP 的良好选择性与 CL 的高灵敏度结合在一起。该 CL 体系的线性范围为 0.1 至 40 μM，水中 4-硝基苯酚的检测限（DL）可达 76 nM。该方法还用于实际水样中，回收率可在 91-96%范围内。
