Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
Department of pharmaceutical analytical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
J Fluoresc. 2024 Jan;34(1):119-138. doi: 10.1007/s10895-023-03276-2. Epub 2023 May 24.
Nanotechnology has emerged as one of the most potential areas for pharmaceutical analysis. The need for nanomaterials in pharmaceutical analysis is comprehended in terms of economic challenges, health and safety concerns. Quantum dots (QDs)or colloidal semiconductor nanocrystals are new groups of fluorescent nanoparticles that bind nanotechnology to drug analysis. Because of their special physicochemical characteristics and small size, QDs are thought to be promising candidates for the electrical and luminescent probes development. They were originally developed as luminescent biological labels, but are now discovering new analytical chemistry applications, where their photo-luminescent properties are used in pharmaceutical, clinical analysis, food quality control and environmental monitoring. In this review, we discuss QDs regarding properties and advantages, advances in methods of synthesis and their recent applications in drug analysis in the recent last years.
纳米技术已成为药物分析中最具潜力的领域之一。从经济挑战、健康和安全问题的角度来看，药物分析中对纳米材料的需求是可以理解的。量子点（QD）或胶体半导体纳米晶体是一类新的荧光纳米粒子，将纳米技术与药物分析结合在一起。由于其特殊的物理化学特性和小尺寸，QD 被认为是电致发光和发光探针发展的有前途的候选者。它们最初是作为发光生物标记物开发的，但现在正在发现新的分析化学应用，其光致发光特性用于药物、临床分析、食品质量控制和环境监测。在这篇综述中，我们讨论了 QD 的性质和优点、合成方法的进展以及近年来在药物分析中的最新应用。
