University of Medicine and Pharmacy, Faculty of Pharmacy, Petru Rares, 4, 200349, Craiova, Romania.
J Pharm Biomed Anal. 2011 Jan 5;54(1):1-12. doi: 10.1016/j.jpba.2010.07.013. Epub 2010 Jul 17.
This paper reviews gas and liquid chromatographic methods for screening, identification and quantification of local anesthetics and/or their metabolites in biological samples. Basic information about sample preparation, separation, detection, and quantification of each procedure is summarised. The pros and cons of the various procedures are critically discussed.
本文综述了用于筛选、鉴定和定量生物样品中局部麻醉剂和/或其代谢物的气、液相色谱方法。总结了每个步骤的样品制备、分离、检测和定量的基本信息。并对各种方法的优缺点进行了批判性讨论。