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显著癌症预防因子提取:关联规则发现方法。

Significant cancer prevention factor extraction: an association rule discovery approach.

机构信息

School of Computing Sciences, Central Queensland University, Queensland, Australia.

出版信息

J Med Syst. 2011 Jun;35(3):353-67. doi: 10.1007/s10916-009-9372-8. Epub 2009 Oct 3.

DOI:10.1007/s10916-009-9372-8
PMID:20703554
Abstract

Cancer is increasing the total number of unexpected deaths around the world. Until now, cancer research could not significantly contribute to a proper solution for the cancer patient, and as a result, the high death rate is uncontrolled. The present research aim is to extract the significant prevention factors for particular types of cancer. To find out the prevention factors, we first constructed a prevention factor data set with an extensive literature review on bladder, breast, cervical, lung, prostate and skin cancer. We subsequently employed three association rule mining algorithms, Apriori, Predictive apriori and Tertius algorithms in order to discover most of the significant prevention factors against these specific types of cancer. Experimental results illustrate that Apriori is the most useful association rule-mining algorithm to be used in the discovery of prevention factors.

摘要

癌症正在增加全球意外死亡的总数。到目前为止,癌症研究还不能为癌症患者提供有效的解决方案,因此,高死亡率仍未得到控制。本研究旨在提取特定类型癌症的显著预防因素。为了找出这些预防因素,我们首先通过广泛的文献回顾,构建了一个膀胱癌、乳腺癌、宫颈癌、肺癌、前列腺癌和皮肤癌的预防因素数据集。随后,我们采用了三种关联规则挖掘算法,即 Apriori、Predictive apriori 和 Tertius 算法,以发现针对这些特定类型癌症的大部分显著预防因素。实验结果表明,Apriori 是发现预防因素时最有用的关联规则挖掘算法。

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本文引用的文献

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Awareness of prostate cancer among patients and the general public: results of an international survey.前列腺癌患者和公众的认知:一项国际调查结果。
Prostate Cancer Prostatic Dis. 2009;12(4):347-54. doi: 10.1038/pcan.2009.30. Epub 2009 Jul 21.
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Height and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial.前列腺、肺、结肠直肠和卵巢癌筛查试验中身高与前列腺癌风险的关系
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Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers.
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Melanoma Detection Using Spatial and Spectral Analysis on Superpixel Graphs.基于超像素图的空间和光谱分析的黑色素瘤检测。
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Fluvoxamine treatment response prediction in obsessive-compulsive disorder: association rule mining approach.强迫症中氟伏沙明治疗反应的预测:关联规则挖掘方法
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Comorbidity Study of Attention-deficit Hyperactivity Disorder (ADHD) in Children: Applying Association Rule Mining (ARM) to Korean National Health Insurance Data.儿童注意力缺陷多动障碍(ADHD)的共病研究:将关联规则挖掘(ARM)应用于韩国国民健康保险数据。
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10
Predicting Metabolic Syndrome Using the Random Forest Method.使用随机森林方法预测代谢综合征
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对吸烟成瘾者和戒烟者肺癌发生的化学预防。
Nat Rev Cancer. 2009 Jul;9(7):476-88. doi: 10.1038/nrc2674.
4
Cancer prevention research - then and now.癌症预防研究——过去与现在。
Nat Rev Cancer. 2009 Jul;9(7):508-16. doi: 10.1038/nrc2646. Epub 2009 Jun 18.
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Anticancer effects of phytosterols.植物甾醇的抗癌作用。
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