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利用皮肤表面电势进行乳腺癌检测——使用生物场诊断系统获得的初步临床试验结果。

The use of skin surface electropotentials for breast cancer detection--preliminary clinical trial results obtained using the biofield diagnostic system.

机构信息

School of Mechanical and Aerospace Engineering, College of Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore.

出版信息

J Med Syst. 2011 Feb;35(1):79-86. doi: 10.1007/s10916-009-9343-0. Epub 2009 Aug 8.


DOI:10.1007/s10916-009-9343-0
PMID:20703583
Abstract

The purpose of this study is to evaluate the efficiency of the Biofield Diagnostic System (BDS) as an adjunct to established diagnostic techniques such as mammography and ultrasound in differentiating benign and malignant breast lesions. The clinical trial was conducted at the Tan Tock Seng hospital, Singapore. 103 women scheduled for mammography and/or ultrasound tests participated in the study. The BDS test recorded a sensitivity of 100%, specificity of 97.6%, and an accuracy of 98.1%. The area under the ROC curve was 0.988 which was slightly lower than that of ultrasound (0.994) and slightly higher than that of mammography (0.951). The BDS test has demonstrated high sensitivity and specificity values in the studied population. The accuracy is also comparable to that of diagnostic techniques like mammography and ultrasound. Thus, it is evident that BDS can be a fast and reliable adjunct tool for getting a secondary opinion on lesions with indeterminate mammographic and sonographic results.

摘要

本研究旨在评估生物场诊断系统 (BDS) 在辅助诸如乳房 X 光摄影和超声等既定诊断技术区分良性和恶性乳房病变方面的效率。该临床试验在新加坡陈笃生医院进行。103 名计划接受乳房 X 光摄影和/或超声检查的女性参与了该研究。BDS 测试的灵敏度为 100%,特异性为 97.6%,准确性为 98.1%。ROC 曲线下面积为 0.988,略低于超声(0.994),略高于乳房 X 光摄影(0.951)。BDS 测试在研究人群中表现出较高的灵敏度和特异性值。准确性也与乳房 X 光摄影和超声等诊断技术相当。因此,BDS 显然可以成为一种快速可靠的辅助工具,用于对具有不确定乳房 X 光摄影和超声结果的病变获得二次意见。

相似文献

[1]
The use of skin surface electropotentials for breast cancer detection--preliminary clinical trial results obtained using the biofield diagnostic system.

J Med Syst. 2009-8-8

[2]
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[3]
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[4]
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引用本文的文献

[1]
Wavelet-based multifractal analysis of dynamic infrared thermograms to assist in early breast cancer diagnosis.

Front Physiol. 2014-5-8

[2]
Evaluation of the efficiency of biofield diagnostic system in breast cancer detection using clinical study results and classifiers.

J Med Syst. 2010-2-23

本文引用的文献

[1]
Bioimpedance tomography (electrical impedance tomography).

Annu Rev Biomed Eng. 2006

[2]
Prospective study of electrical impedance scanning for identifying young women at risk for breast cancer.

Breast Cancer Res Treat. 2006-5

[3]
Electrical impedance scanning for the early detection of breast cancer in young women: preliminary results of a multicenter prospective clinical trial.

J Clin Oncol. 2005-4-20

[4]
Technology review: the use of electrical impedance scanning in the detection of breast cancer.

Breast Cancer Res. 2004

[5]
A framework for early discovery of breast tumor using thermography with artificial neural network.

Breast J. 2003

[6]
Time-domain optical mammography: initial clinical results on detection and characterization of breast tumors.

Appl Opt. 2003-6-1

[7]
Individual and combined effects of age, breast density, and hormone replacement therapy use on the accuracy of screening mammography.

Ann Intern Med. 2003-2-4

[8]
A review of electrical impedance techniques for breast cancer detection.

Med Eng Phys. 2003-3

[9]
Initial in vivo experience with steady-state subzone-based MR elastography of the human breast.

J Magn Reson Imaging. 2003-1

[10]
Electropotential measurements as a new diagnostic modality for breast cancer.

Lancet. 1998-8-1

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