Group Health Research Institute, Seattle, WA 98101-1448, USA.
Med Care. 2010 Sep;48(9):815-20. doi: 10.1097/MLR.0b013e3181e57918.
We sought to estimate the direct cost, from the perspective of the health insurer or purchaser, of breast-care services in the year following a false positive screening mammogram compared with a true negative examination.
We identified 21,125 women aged 40 to 80 years enrolled in an integrated healthcare delivery system in Washington State, who participated in screening mammography between January 1, 1998 and July 30, 2002. Pathology and cancer registry data were used to identify breast cancer diagnoses in the year following the screening mammogram. A positive examination was defined as a Breast Imaging Reporting and Data System assessment of 0, 4, or 5. Women with a positive screening mammogram but no breast cancer diagnosed within 1 year were classified as false positives. We used diagnostic and procedure codes in automated health plan data to identify services received in the year following the screening mammogram. Medicare reimbursement rates were applied to all services. We used ordinary least-squares linear regression to estimate the difference in costs following a false positive versus true negative screening mammogram.
False positive results occurred in 9.9% of women; most false positives (87.3%) were followed by breast imaging only. The mean cost of breast-care following a false positive mammogram was $527. This was $503 (95% confidence interval, $490-$515) more than the cost of breast-care services for true negative women.
The direct costs for breast-related procedures following false positive screening mammograms may contribute substantially to US healthcare spending.
我们旨在从保险公司或购买者的角度,估算在经过假阳性筛检乳房 X 光摄影检查后一年中,乳房护理服务的直接成本与真正阴性检查相比。
我们在华盛顿州一个综合医疗服务提供系统中确定了 21,125 名年龄在 40 至 80 岁之间的女性,这些女性在 1998 年 1 月 1 日至 2002 年 7 月 30 日期间参与了筛检乳房 X 光摄影。病理学和癌症登记数据用于确定在筛检乳房 X 光摄影后的一年内乳腺癌的诊断。阳性检查被定义为乳房成像报告和数据系统评估为 0、4 或 5。在一年内未诊断出乳腺癌但筛检乳房 X 光摄影呈阳性的女性被归类为假阳性。我们使用自动健康计划数据中的诊断和程序代码来确定在筛检乳房 X 光摄影后一年内接受的服务。所有服务均适用医疗保险报销费率。我们使用普通最小二乘法线性回归来估算假阳性与真正阴性筛检乳房 X 光摄影后成本的差异。
假阳性结果出现在 9.9%的女性中;大多数假阳性(87.3%)仅接受乳房成像检查。假阳性乳房 X 光摄影后乳房护理的平均费用为 527 美元。这比真正阴性女性的乳房护理服务费用多 503 美元(95%置信区间,490-515 美元)。
假阳性筛检乳房 X 光摄影后与乳房相关的程序的直接成本可能会对美国的医疗保健支出产生重大影响。