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解析藻类脂质代谢:基因鉴定的最新进展。

Unraveling algal lipid metabolism: Recent advances in gene identification.

机构信息

Microalgal Biotechnology Laboratory, French Associates Institute for Agriculture and Biotechnology of Drylands, Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, Midreshet Ben-Gurion 84990, Israel.

出版信息

Biochimie. 2011 Jan;93(1):91-100. doi: 10.1016/j.biochi.2010.07.020. Epub 2010 Aug 13.

Abstract

Microalgae are now the focus of intensive research due to their potential as a renewable feedstock for biodiesel. This research requires a thorough understanding of the biochemistry and genetics of these organisms' lipid-biosynthesis pathways. Genes encoding lipid-biosynthesis enzymes can now be identified in the genomes of various eukaryotic microalgae. However, an examination of the predicted proteins at the biochemical and molecular levels is mandatory to verify their function. The essential molecular and genetic tools are now available for a comprehensive characterization of genes coding for enzymes of the lipid-biosynthesis pathways in some algal species. This review mainly summarizes the novel information emerging from recently obtained algal gene identification.

摘要

由于微藻有可能成为生物柴油的可再生原料,因此目前正在对其进行深入研究。这项研究需要深入了解这些生物体脂质生物合成途径的生物化学和遗传学。现在可以从各种真核微藻的基因组中鉴定出编码脂质生物合成酶的基因。然而,为了验证其功能,必须在生化和分子水平上检查预测的蛋白质。目前已经有了必要的分子和遗传工具,可以对某些藻类物种中脂质生物合成途径的酶编码基因进行全面表征。这篇综述主要总结了最近从藻类基因鉴定中获得的新信息。

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