Department of Kinesiology, University of Texas at El Paso, El Paso, Texas 79902, USA.
Endocr Res. 2010;35(3):95-105. doi: 10.3109/07435800.2010.496088.
The purpose was to evaluate the relationships between fasting serum leptin, resting metabolic rate (RMR), and body composition in premenopausal Hispanic and non-Hispanic White (White) women.
Participants were 67 Hispanic and 43 White women who arrived at the laboratory in a fasted state for measurement of RMR by indirect calorimetry, bone mineral content measured by dual-energy X-ray absorptiometry, and body density measured by hydrodensitometry. Serum leptin levels were determined by EIA.
Multiple regression analysis revealed that body mass and lean body mass were the best predictors of RMR. Leptin was not a significant predictor of RMR.
Further research needs to be done to examine the role of leptin on metabolism, especially in ethnic groups predisposed to development of obesity and related disorders.
评估绝经前西班牙裔和非西班牙裔白种（白种）女性空腹血清瘦素、静息代谢率（RMR）和身体成分之间的关系。
参与者为 67 名西班牙裔和 43 名白种女性，她们空腹到达实验室，通过间接热量法测量 RMR、双能 X 射线吸收法测量骨矿物质含量以及比重计法测量体密度。通过 EIA 测定血清瘦素水平。
多元回归分析显示，体重和瘦体重是 RMR 的最佳预测因子。瘦素不是 RMR 的重要预测因子。
需要进一步研究以检查瘦素对代谢的作用，特别是在易发生肥胖和相关疾病的种族群体中。
