Min Jung-Ah, Lee KyeSeong, Ki Dai-Jin
Department of Psychiatry, Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea.
Curr Drug Abuse Rev. 2010 Jun;3(2):110-5. doi: 10.2174/1874473711003020110.
Despite the high prevalence and economic burden, biological mechanisms and effective treatments of alcohol hangover are not well understood. We have focused on oxidative stress and inflammatory responses which would substantially contribute to hangover physiology and symptoms based on preexisting research data. And, it is considered that minerals are one of the important components and influencing factors in antioxidant and anti-inflammatory system. Moreover, mineral deficient conditions show similar symptoms that occur in alcohol hangover. Herein we review some possible implications of various minerals, such as selenium, zinc, copper, vanadium, iron, and magnesium, according to suggested mechanisms and symptoms of alcohol hangover. Although, noticeable considerations and controlled trials will be required for general recommendations, we hope that our preliminary speculation would pave the way for further understanding and managing alcohol hangover.
尽管酒精宿醉的患病率很高且经济负担沉重，但其生物学机制和有效治疗方法仍未得到充分了解。基于先前的研究数据，我们聚焦于氧化应激和炎症反应，它们对宿醉生理和症状有重大影响。并且，矿物质被认为是抗氧化和抗炎系统的重要组成部分和影响因素之一。此外，矿物质缺乏的情况表现出与酒精宿醉相似的症状。在此，我们根据酒精宿醉的推测机制和症状，综述了各种矿物质（如硒、锌、铜、钒、铁和镁）的一些可能影响。尽管要给出一般性建议还需要显著的考量和对照试验，但我们希望我们的初步推测能为进一步理解和管理酒精宿醉铺平道路。
