Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Magn Reson Med. 2010 Oct;64(4):967-74. doi: 10.1002/mrm.22575.
The transverse relaxation rate (R(2)) of fresh human blood has been investigated at high and ultrahigh field, to characterize the R(2) dependency on blood sample oxygenation, hematocrit, and Carr-Purcell Meiboom-Gill sequence inter-echo spacing. Data were fitted to chemical exchange and diffusion models to assess their performance at different field strengths. The diffusion model gave a slightly superior fit at both field strengths, but the difference is unlikely to be relevant for the signal to noise ratio achieved in most in vivo experiments. Fitted model parameters were similar to those found in literature.
本研究在高场和超高场下对新鲜人血的横向弛豫率（R(2)）进行了研究，以表征 R(2) 对血样氧合、红细胞压积和 Carr-Purcell Meiboom-Gill 序列回波间隔的依赖性。数据拟合到化学交换和扩散模型，以评估它们在不同场强下的性能。扩散模型在两种场强下的拟合效果都略好，但由于在大多数体内实验中获得的信噪比，这种差异不太可能具有相关性。拟合模型参数与文献中的参数相似。
