Department of Medicine, IRCCS Istituto Clinico Humanitas, Rozzano, Italy.
Autoimmun Rev. 2010 Oct;9(12):795-800. doi: 10.1016/j.autrev.2010.08.008. Epub 2010 Aug 15.
The number of 2009 publications in indexed journals dealing with 'autoimmunity' has maintained its increasing trend compared to the previous five years. Numerous developments have been proposed in our understanding of systemic and organ-specific autoimmune diseases (particularly multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis) and of basic autoimmunity mechanisms (particularly Th17, T regulatory cells, and autoantibodies). Both these lines of evidence share a significant potential to be translated into new therapeutic options to impact clinical practice. This article will discuss selected publications from prominent scientific journals dedicated to immunology and autoimmunity and ultimately include some expectations in branches of autoimmunity that appear promising for future developments.
与前五年相比，索引期刊中涉及“自身免疫”的 2009 年出版物数量保持了增长趋势。我们对系统性和器官特异性自身免疫性疾病（特别是多发性硬化症、系统性红斑狼疮和类风湿性关节炎）以及基础自身免疫机制（特别是 Th17、T 调节细胞和自身抗体）的理解有了很多新的进展。这两方面的证据都具有很大的潜力转化为新的治疗选择，以影响临床实践。本文将讨论免疫学和自身免疫领域一些著名科学期刊的精选出版物，并最终包括一些在自身免疫领域有希望取得未来发展的分支的预期。
