Department of Surgery, East and North Hertforshire NHS Trust, Hertfordshire, AL7 4HQ, UK.
Diagn Pathol. 2010 Aug 18;5:53. doi: 10.1186/1746-1596-5-53.
Inflammatory myofibroblastic pseudotumours of the liver are rare tumour-like lesions that can mimic malignant liver neoplasms. The symptoms and radiological findings of this rare tumour can pose diagnostic difficulties. We describe a 69-year-old gentleman who was admitted to our department with symptoms suggestive of acute cholecystitis. Ultrasonography and computed tomography of the liver raised the possibility of metastatic liver disease. A core biopsy of the liver was performed to confirm the diagnosis of liver metastasis. Unexpectedly it showed no evidence of malignancy but instead revealed an inflammatory myofibroblastic pseudotumour of the liver. This case report highlights the diagnostic dilemma that arose due to the similarity of appearances between the two pathological entities on imaging and this stresses the need for accurate histological diagnosis so as to avoid unnecessary surgical intervention. To the best of our knowledge, only a minority of cases are reported in the literature associating a hepatic inflammatory myofibroblastic pseudotumour with gall stones.
肝脏炎性肌纤维母细胞瘤样假肿瘤是一种罕见的肿瘤样病变,可模拟恶性肝肿瘤。这种罕见肿瘤的症状和影像学表现可能会造成诊断困难。我们描述了一位 69 岁的男性,他因疑似急性胆囊炎入院。肝脏的超声和 CT 检查提示转移性肝病的可能。进行了肝活检以明确肝转移的诊断。但令人意外的是,活检并未显示恶性肿瘤的证据,而是显示为肝脏炎性肌纤维母细胞瘤样假肿瘤。本病例报告强调了由于两种病理实体在影像学上的相似性而导致的诊断难题,这强调了准确的组织学诊断的必要性,以避免不必要的手术干预。据我们所知,文献中只有少数病例报告将肝炎性肌纤维母细胞瘤样假肿瘤与胆结石联系在一起。