Lee S-H, Fang Y-C, Luo J-P, Kuo H-I, Chen H-C
Taipei Municipal Hoping Hospital, 33 Section 2 Chung-Hwa Road, Taipei, Taiwan.
J Clin Pathol. 2003 Nov;56(11):868-70. doi: 10.1136/jcp.56.11.868.
Inflammatory pseudotumour is an uncommon mass forming lesion, representing the histological expression of an infective or reactive/reparative process (pseudotumour) in most cases, and a bona fide neoplasm (for example, inflammatory myofibroblastic tumour) in a minority of cases. This report describes the case of an inflammatory pseudotumour with a pathology that unveiled proliferative CD68 positive and actin negative spindle shaped cells, with a mild mixed inflammatory infiltrate, and a culture that yielded an uncommon fastidious bacillus, Eikenella corrodens. The clinical course was indolent but protracted, with insidious progression to multifocal non-contiguous lesions, involving the lungs, liver, spleen, left kidney, and deep neck tissue, all of which responded to medical treatment with appropriate antibiotics. It is of paramount importance that clinicians search for an infective cause of an inflammatory pseudotumour, to ensure appropriate treatment.
炎性假瘤是一种罕见的形成肿块的病变,在大多数情况下代表感染性或反应性/修复性过程(假瘤)的组织学表现,少数情况下代表真正的肿瘤(例如炎性肌纤维母细胞瘤)。本报告描述了一例炎性假瘤病例,其病理显示增殖的CD68阳性且肌动蛋白阴性的梭形细胞,伴有轻度混合性炎性浸润,培养物培养出一种罕见的苛养菌——腐蚀艾肯菌。临床病程进展缓慢但持续时间长,隐匿性发展为多灶性不连续病变,累及肺、肝、脾、左肾和深部颈部组织,所有这些病变对抗生素治疗均有反应。临床医生寻找炎性假瘤的感染原因以确保恰当治疗至关重要。