Tramu G, Beauvillain J C, Mazzuca M, Linquette M, Lefebvre J, Fossati P, Christiaens J L
Ann Endocrinol (Paris). 1978;39(1):51-2.
In one case of pituitary basophil adenoma, the majority of the cells contains numerous small granulations which, by using immunohistoenzymatic technique, react with alpha, 17-39 ACTH and beta, MSH antisera. The reaction with anti beta, 1-24 ACTH is negative. The radioimmunoassay of ACTH reveals an increase of plasmatic ACTH, but the cortisol cycle stays low. This data suggests that this functional adenoma releases a product of which has an immunological relationship with ACTH, without biological activity.
在一例垂体嗜碱性细胞瘤中，大多数细胞含有大量小颗粒，通过免疫组织化学技术，这些颗粒与α-促肾上腺皮质激素（ACTH）17 - 39和β-促黑素（MSH）抗血清发生反应。与抗β-促肾上腺皮质激素1 - 24的反应为阴性。促肾上腺皮质激素的放射免疫测定显示血浆促肾上腺皮质激素增加，但皮质醇循环水平较低。这些数据表明，这种功能性腺瘤释放出一种与促肾上腺皮质激素有免疫关系但无生物活性的产物。
