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嗜碱性和嫌色性垂体腺瘤的免疫细胞化学相似性。13例病例的光镜和电镜研究(作者译)

[Immunocytochemical similarities between basophilic and chromophobe pituitary adenomas. Light and electron microscopic study of 13 cases (author's transl)].

作者信息

Hassoun J, Charpin C, Jaquet P, Oliver C, Lissitzky J C, Grisoli F, Toga M

出版信息

Ann Endocrinol (Paris). 1979;40(6):559-60.

PMID:232835
Abstract

ACTH, beta MSH, beta LPH, beta endorpSin, leucine and methionine enkephalin activities were tested in four Cushing pituitary basophilic adenomas and nine "chromophobe" adenomas with immunoperoxidase methods. The antisera gave various positive reactions in both of these groups. ACTH, alpha MSH and enkephalins were predominant. The reason why these hormones are clinically silent in "chromophobe" or, even, basophilic adenomas is still to be elucidated.

摘要

采用免疫过氧化物酶法检测了4例库欣垂体嗜碱性腺瘤和9例“嫌色细胞”腺瘤中的促肾上腺皮质激素(ACTH)、β-促黑素(β-MSH)、β-促脂解素(β-LPH)、β-内啡肽、亮氨酸脑啡肽和甲硫氨酸脑啡肽活性。抗血清在这两组中均产生了不同的阳性反应。ACTH、α-MSH和脑啡肽占主导。这些激素在“嫌色细胞”腺瘤甚至嗜碱性腺瘤中临床上无表现的原因仍有待阐明。

相似文献

1
[Immunocytochemical similarities between basophilic and chromophobe pituitary adenomas. Light and electron microscopic study of 13 cases (author's transl)].嗜碱性和嫌色性垂体腺瘤的免疫细胞化学相似性。13例病例的光镜和电镜研究(作者译)
Ann Endocrinol (Paris). 1979;40(6):559-60.
2
[Pituitary adenomas with cells containing bêta MSH, alpha and bêta endorphins and without ACTH (author's transl)].含β促黑素、α和β内啡肽且无促肾上腺皮质激素的垂体腺瘤(作者译)
Ann Endocrinol (Paris). 1979;40(6):561-2.
3
Corticolipotropin immunoreactivity in silent chromophobe adenomas: a light and electron microscopic study.无功能嫌色细胞腺瘤中的促肾上腺皮质激素释放素免疫反应性:光镜和电镜研究
Arch Pathol Lab Med. 1982 Jan;106(1):25-30.
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[Pituitary adenoma with alpha, 17-39 ACTH and beta, MSH cells, without hypercorticism (author's transl)].伴有α、17 - 39促肾上腺皮质激素及β、促黑素细胞的垂体腺瘤,无皮质醇增多症(作者译)
Ann Endocrinol (Paris). 1978;39(1):51-2.
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Silent corticotropic adenomas of the human pituitary gland: a histologic, immunocytologic, and ultrastructural study.人垂体的静默促肾上腺皮质激素腺瘤:一项组织学、免疫细胞化学及超微结构研究
Am J Pathol. 1980 Mar;98(3):617-38.
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ACTH LPH and related peptides in the ectopic ACTH syndrome.异位促肾上腺皮质激素(ACTH)综合征中的促肾上腺皮质激素、促脂解素及相关肽
Clin Endocrinol (Oxf). 1980 Nov;13(5):437-45. doi: 10.1111/j.1365-2265.1980.tb03409.x.
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Immunohistochemical and immunoelectron-microscopic study of pituitary adenomas associated with Cushing's disease. A report of 13 cases.库欣病相关垂体腺瘤的免疫组织化学和免疫电子显微镜研究。13例报告。
Am J Pathol. 1982 Oct;109(1):1-7.
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Evidence for the presence of pro-gamma-melanotropin, the NH2-terminal fragment of the corticotropin-beta-lipotropin precursor, in corticotropin-producing tumours.促肾上腺皮质激素生成肿瘤中存在促γ-促黑素(促肾上腺皮质激素-β-促脂素前体的氨基末端片段)的证据。
Virchows Arch A Pathol Anat Histol. 1981;394(1-2):143-50. doi: 10.1007/BF00431672.
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[Immunocytologic analysis, in rat hypothalamus, of neurons producing peptides related to endorphin, ACTH, MSH and beta-LPH. Comparison with other peptidergic and monoaminergic neurons].[大鼠下丘脑内产生与内啡肽、促肾上腺皮质激素、促黑素细胞激素和β-促脂解素相关肽的神经元的免疫细胞分析。与其他肽能和单胺能神经元的比较]
C R Seances Soc Biol Fil. 1979;173(4):719-24.
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Proopiolipomelanocortin peptides in normal pituitary, pituitary tumor, and plasma of normal and Cushing's horses.正常垂体、垂体肿瘤以及正常马和库欣氏马血浆中的促阿片-促黑素细胞皮质素原肽
Endocrinology. 1982 Mar;110(3):941-54. doi: 10.1210/endo-110-3-941.

引用本文的文献

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Perioperative hypothalamic pituitary adrenal function in patients with silent corticotroph adenomas.无症状促肾上腺皮质激素腺瘤患者围手术期下丘脑-垂体-肾上腺功能。
Pituitary. 2017 Aug;20(4):471-476. doi: 10.1007/s11102-017-0809-7.
2
Elevated proenkephalin-derived peptide levels in ACTH-producing adenomas: nucleus and cytoplasm localization.促肾上腺皮质激素分泌腺瘤中脑啡肽原衍生肽水平升高:细胞核与细胞质定位
Endocrine. 1998 Jun;8(3):231-40. doi: 10.1385/ENDO:8:3:231.
3
Proliferation of adenohypophyseal cells into posterior lobe. Their normal anatomical condition and possible neoplastic potentiality.
腺垂体细胞向后叶增殖。它们的正常解剖状况及可能的肿瘤形成潜能。
Acta Neurochir (Wien). 1990;104(1-2):21-6. doi: 10.1007/BF01842888.