含β促黑素、α和β内啡肽且无促肾上腺皮质激素的垂体腺瘤（作者译）
[Pituitary adenomas with cells containing bêta MSH, alpha and bêta endorphins and without ACTH (author's transl)].
作者信息
Tramu G, Beauvillain J C, Mazzuca M, Girard F, Laine E, Christiaens J L, Wemeau J L, Fossati P, Linquette M
出版信息
Ann Endocrinol (Paris). 1979;40(6):561-2.
PMID:232836
Abstract
By using immunohistoenzymatic techniques, cells of 4 pituitary adenomas are revealed with beta MSH, alpha and beta endorphins antisera but do not react with 1--24 and 17--39 ACTH antisera. These data suggest that adenomatous cells are able to synthesize and LPH-like molecule without ACTH. The levels of plasmatic LPH and beta MSH, studied by RIA, stay normal. These results are discussed.
摘要
通过免疫组织酶技术，发现4例垂体腺瘤细胞与β-促黑素、α和β-内啡肽抗血清发生反应，但不与1-24和17-39促肾上腺皮质激素抗血清反应。这些数据表明腺瘤细胞能够在不产生促肾上腺皮质激素的情况下合成类促脂解素分子。通过放射免疫分析研究的血浆促脂解素和β-促黑素水平保持正常。对这些结果进行了讨论。
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