The Autonomic Laboratory, Neurologic Institute, University Hospitals Case Medical Center, Cleveland, OH, USA.
J Pediatr. 2011 Jan;158(1):20-3. doi: 10.1016/j.jpeds.2010.07.005. Epub 2010 Aug 17.
To investigate the frequency of various nonorthostatic complaints in children with postural orthostatic tachycardia syndrome (POTS).
We used our autonomic laboratory database to identify all pediatric patients with traditionally defined POTS who had completed the Ohio Dysautonomia Survey (ODYSA). The responses of the patients to questions targeting various autonomic complaints, including syncope, gastrointestinal symptoms, sleep disturbances, headaches, urinary symptoms, chronic pain, and Raynaud-like symptoms, were collected and analyzed.
A total of 53 pediatric patients completed the ODYSA questionnaire. The participants reported high frequencies of sleep abnormalities, chronic pain, Raynaud-like symptoms, and gastrointestinal abnormalities, with lower rates of headaches, syncope, and urinary complaints.
Our findings demonstrate the occurrence of various nonorthostatic symptoms in pediatric patients with POTS. These findings suggest the need for an interdisciplinary approach to the treatment and management of POTS, as well as for further investigation into the mechanisms that lead to the concurrent presentation of both orthostatic and nonorthostatic symptoms in these patients.
调查体位性心动过速综合征（POTS）患儿各种非直立性症状的发生频率。
我们使用自主神经实验室数据库，确定了所有完成俄亥俄自主神经疾病调查（ODYSA）的传统定义为 POTS 的儿科患者。收集并分析了患者对各种自主神经症状（包括晕厥、胃肠道症状、睡眠障碍、头痛、泌尿系统症状、慢性疼痛和雷诺样症状）问题的回答。
共有 53 名儿科患者完成了 ODYSA 问卷。参与者报告了睡眠异常、慢性疼痛、雷诺样症状和胃肠道异常的高频率，而头痛、晕厥和泌尿系统症状的发生率较低。
我们的研究结果表明，POTS 患儿存在各种非直立性症状。这些发现表明，需要采用跨学科方法来治疗和管理 POTS，还需要进一步研究导致这些患者同时出现直立性和非直立性症状的机制。
