Davis Erica C, Callender Valerie D
J Clin Aesthet Dermatol. 2010 Apr;3(4):24-38.
Acne vulgaris is one of the most common conditions for which all patients, including those with skin of color (Fitzpatrick skin types IV-VI), seek dermatological care. The multifactorial pathogenesis of acne appears to be the same in ethnic patients as in Caucasians. However, there is controversy over whether certain skin biology characteristics, such as sebum production, differ in ethnic patients. Clinically, acne lesions can appear the same as those seen in Caucasians; however, histologically, all types of acne lesions in African Americans can be associated with intense inflammation including comedones, which can also have some degree of inflammation. It is the sequelae of the disease that are the distinguishing characteristics of acne in skin of color, namely postinflammatory hyperpigmentation and keloidal or hypertrophic scarring. Although the medical and surgical treatment options are the same, it is these features that should be kept in mind when designing a treatment regimen for acne in skin of color.
寻常痤疮是所有患者(包括有色人种患者,即 Fitzpatrick 皮肤分型为 IV - VI 型者)寻求皮肤科治疗的最常见病症之一。痤疮的多因素发病机制在种族患者和白种人中似乎相同。然而,对于某些皮肤生物学特征(如皮脂分泌)在种族患者中是否存在差异存在争议。临床上,痤疮皮损可能与白种人所见的皮损相同;然而,在组织学上,非裔美国人的所有类型痤疮皮损都可能伴有强烈炎症,包括粉刺,粉刺也可能有一定程度的炎症。正是该疾病的后遗症才是有色人种皮肤痤疮的显著特征,即炎症后色素沉着以及瘢痕疙瘩或增生性瘢痕。尽管药物和手术治疗选择相同,但在为有色人种皮肤的痤疮设计治疗方案时应牢记这些特征。