Sugiyama T, Itho M, Katho N, Sahashi M, Watanabe J, Yamada S, Kamihira O, Mizutani K, Ono Y
Department of Urology, Shizuoka Saiseikai General Hospital.
Nihon Hinyokika Gakkai Zasshi. 1991 Mar;82(3):462-6. doi: 10.5980/jpnjurol1989.82.462.
Ninety-four kidneys with renal stones less than or equal to 20 mm in diameter were treated by extracorporeal shock wave litotripsy (ESWL) using a Dornier modified HM3 lithotripter and the results were compared with those of 98 kidneys with similar size stones treated with a Dornier HM3 lithotripter. The Dornier modified HM3 lithotripter is equipped with a new type of shock wave generator with a reduced capacity for 30% less pressure peakes at the same voltage. It has an enlarged ellipsoid leading to a smaller focus and a reduced pressure per area at the shock wave entry into the skin. All treatments of modified HM3 litotripter series were performed under only intravenous analgosedation, without epidural anesthesia. The number of shock waves in the modified HM3 series ranged 900 to 6000, with the mean values of 2863 +/- 1234, which was 1.55 times as that in the Dornier HM3 series. Complete disintegration was achieved in 94 of 94 modified HM3 series kidneys and 98 of 98 kidneys of HM3 series. Complete removal of the stone was done at 72.6% in the modified HM3 series and at 70.4% in the HM3 series 3 months after ESWL. There were no severe complications in both modified HM3 series and HM3 series. Renal damage caused by ESWL was monitored by the level of urinary enzyme, N-acetyl-beta-glucosaminidase (NAG) and beta 2 microglobulin (beta 2MG) and the level of urinary protein. The levels of NAG, beta 2MG and urinary protein in the HM3 series were higher than those of the modified HM3 series.(ABSTRACT TRUNCATED AT 250 WORDS)
使用多尼尔改良HM3碎石机对94例直径小于或等于20毫米肾结石患者的肾脏进行体外冲击波碎石术(ESWL)治疗,并将结果与使用多尼尔HM3碎石机治疗的98例肾结石大小相似的肾脏患者进行比较。多尼尔改良HM3碎石机配备了新型冲击波发生器,在相同电压下压力峰值降低30%。它有一个扩大的椭圆体,导致焦点变小,冲击波进入皮肤时单位面积压力降低。改良HM3碎石机系列的所有治疗仅在静脉镇痛镇静下进行,无需硬膜外麻醉。改良HM3系列的冲击波次数为900至6000次,平均值为2863±1234次,是多尼尔HM3系列的1.55倍。改良HM3系列94例肾脏和HM3系列98例肾脏结石均完全粉碎。ESWL术后3个月,改良HM3系列结石完全清除率为72.6%,HM3系列为70.4%。改良HM3系列和HM3系列均无严重并发症。通过尿酶N-乙酰-β-氨基葡萄糖苷酶(NAG)、β2微球蛋白(β2MG)水平及尿蛋白水平监测ESWL引起的肾损伤。HM3系列的NAG、β2MG和尿蛋白水平高于改良HM3系列。(摘要截断于250字)