Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
Semin Pediatr Neurol. 2010 Sep;17(3):169-75. doi: 10.1016/j.spen.2010.06.005.
Status epilepticus (SE) is a common pediatric neurologic emergency that refers to a prolonged seizure or recurrent seizures without a return to baseline mental status between seizures. Appropriate treatment strategies are necessary to prevent prolonged SE and its associated morbidity and mortality. This review discusses the importance of a rapid and organized management approach, reviews data related to commonly utilized medications including benzodiazepines, phenytoin, phenobarbital, valproate sodium, and levetiracetam, and then provides a sample SE management algorithm.
癫痫持续状态(SE)是一种常见的儿科神经系统急症,是指发作之间没有恢复到基线精神状态的长时间发作或反复发作。需要采取适当的治疗策略来预防长时间 SE 及其相关的发病率和死亡率。本综述讨论了快速和有组织的管理方法的重要性,回顾了与常用药物(包括苯二氮䓬类、苯妥英钠、苯巴比妥、丙戊酸钠和左乙拉西坦)相关的数据,然后提供了一个 SE 管理算法示例。