Department of Pediatrics and Neurology, Baylor College of Medicine, Houston, TX, USA.
Semin Pediatr Neurol. 2010 Sep;17(3):176-81. doi: 10.1016/j.spen.2010.06.006.
This review discusses the medical management of pediatric refractory status epilepticus, defined here as persistent seizures of any type after the administration of 2 appropriate anticonvulsants. The use of both nonanesthetic and anesthetic anticonvulsants is discussed along with the relative strengths and weaknesses of each agent. Appropriate treatment goals and the use of electroencephalographic monitoring are described as are reasonable treatment algorithms. Finally, ethical considerations are briefly discussed in the context of available outcome data.
这篇综述讨论了儿科难治性癫痫持续状态的医学管理，这里将其定义为在使用 2 种适当的抗癫痫药物后仍持续发作的任何类型的癫痫。讨论了非麻醉性和麻醉性抗癫痫药物的使用，以及每种药物的相对优缺点。描述了适当的治疗目标和脑电图监测的使用，以及合理的治疗方案。最后，根据现有结果数据简要讨论了伦理考虑。
