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溃疡病中的饮食与营养

Diet and nutrition in ulcer disease.

作者信息

Marotta R B, Floch M H

机构信息

Nutrition Support Service, Norwalk Hospital, Connecticut.

出版信息

Med Clin North Am. 1991 Jul;75(4):967-79. doi: 10.1016/s0025-7125(16)30424-2.

DOI:10.1016/s0025-7125(16)30424-2
PMID:2072799
Abstract

In this era of H2-inhibitors, the available evidence does not support the need to place peptic ulcer disease patients on restrictive diets. The major goal of diet is to avoid extreme elevations of gastric acid secretion and the direct irritation of gastric mucosa. In view of this, only slight modifications in the patient's usual diet are recommended. Table 1 depicts a sample menu for chronic peptic ulcer disease. Frequent milk ingestion as previously prescribed is not encouraged. This is owing to the transient buffering effect and significant gastric acid secretion effect of milk. The fat content of milk has no influence on these effects. Spices, in particular black pepper, red pepper, and chili powder, may produce dyspepsia. One study shows red chili powder to have no detrimental effect on duodenal ulcer healing. It has also been proposed that daily pepper ingestion may have a beneficial adaptive cytoprotective response. While still controversial and under evaluation, peptic ulcer patients should avoid any spice that causes discomfort, especially during exacerbation of peptic disease. Currently, studies indicate that it is prudent to avoid alcohol. This is especially true for the concentrated forms, such as 40% (80 proof) alcohol. Coffee should be avoided on the basis of its strong acid secretagogue property. Coffee can induce dyspepsia. Whether noncoffee caffeine-containing beverages (tea, soft drinks) induce peptic ulcer is unknown, but they are acid secretion stimulators. Decaffeinated coffee has an acid stimulating effect as well. It is reasonable to have peptic ulcer patients restrict decaffeinated coffee and all caffeine-containing beverages. There appears to be no evidence to restrict dietary fiber. Some fiber-containing foods may possess factors that are protective against ulcer disease. According to the Mayo Clinic Diet Manual, previously recommended small frequent feedings have not been shown to be more effective than three meals per day in the treatment of chronic peptic ulcer disease. This reference cites authorities advising against extra feedings because of increased acid secretion and unnecessary complication of eating patterns. However, some patients claim to be relieved of symptoms with more frequent feedings, especially during acute phases. Citric acid juices may induce reflux and cause discomfort in selective patients. Stomach distention with large quantities of food should be discouraged. Although there is now little role for dietary therapy, one should note that bland and ulcer diets probably are not detrimental to most persons if they are used for a short time and may have some psychological benefit.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

在这个使用H2抑制剂的时代,现有证据并不支持对消化性溃疡病患者采用限制性饮食。饮食的主要目标是避免胃酸分泌过度升高以及避免对胃黏膜的直接刺激。鉴于此,建议仅对患者的日常饮食做轻微调整。表1展示了一份慢性消化性溃疡病的示例菜单。不鼓励像之前规定的那样频繁摄入牛奶。这是因为牛奶具有短暂的缓冲作用以及显著的胃酸分泌作用。牛奶中的脂肪含量对这些作用没有影响。香料,尤其是黑胡椒、红辣椒和辣椒粉,可能会引发消化不良。一项研究表明红辣椒粉对十二指肠溃疡愈合没有不利影响。也有人提出每日摄入胡椒可能会产生有益的适应性细胞保护反应。虽然仍存在争议且正在评估中,但消化性溃疡患者应避免食用任何会引起不适的香料,尤其是在消化性疾病发作期间。目前,研究表明避免饮酒是明智的。对于浓缩形式的酒,如40%(80度)的酒精,尤其如此。基于咖啡强烈的胃酸分泌促进特性,应该避免饮用。咖啡会引发消化不良。不含咖啡的含咖啡因饮料(茶、软饮料)是否会诱发消化性溃疡尚不清楚,但它们是胃酸分泌刺激物。脱咖啡因咖啡也有刺激胃酸分泌的作用。让消化性溃疡患者限制饮用脱咖啡因咖啡和所有含咖啡因饮料是合理的。似乎没有证据表明需要限制膳食纤维。一些含纤维的食物可能含有对溃疡病有保护作用的成分。根据梅奥诊所饮食手册,之前推荐的少食多餐在治疗慢性消化性溃疡病方面并未被证明比一日三餐更有效。该参考文献引用权威观点,建议不要额外加餐,因为这会增加胃酸分泌并导致饮食模式出现不必要的并发症。然而,一些患者声称少食多餐能缓解症状,尤其是在急性期。在部分患者中,柑橘汁可能会引发反流并造成不适。应避免大量食物使胃部扩张。虽然现在饮食疗法的作用不大,但应该注意的是,如果短期采用清淡和溃疡病饮食,对大多数人可能并无害处,而且可能会有一些心理上的益处。(摘要截选至400字)

相似文献

1
Diet and nutrition in ulcer disease.溃疡病中的饮食与营养
Med Clin North Am. 1991 Jul;75(4):967-79. doi: 10.1016/s0025-7125(16)30424-2.
2
Comparison of coffee intake and coffee-induced symptoms in patients with duodenal ulcer, nonulcer dyspepsia, and normal controls.十二指肠溃疡患者、非溃疡性消化不良患者及正常对照者的咖啡摄入量与咖啡诱发症状的比较。
Am J Gastroenterol. 1990 Oct;85(10):1339-42.
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[The "tricks" of cures - does diet therapy in peptic ulcer still make sense?].[治愈的“诀窍”——消化性溃疡的饮食疗法还有意义吗?]
Ned Tijdschr Geneeskd. 1982 May 1;126(18):821-4.
4
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[Effects of nicotine, alcohol and caffeine on the incidence, healing and recurrence rate of peptic ulcer].[尼古丁、酒精和咖啡因对消化性溃疡发病率、愈合及复发率的影响]
Z Gastroenterol. 1987 Aug;25 Suppl 3:33-40.
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The effect of various forms of milk on gastric-acid secretion. Studies in patients with duodenal ulcer and normal subjects.各种形式的牛奶对胃酸分泌的影响。对十二指肠溃疡患者和正常受试者的研究。
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Eur J Clin Nutr. 1998 Sep;52(9):668-74. doi: 10.1038/sj.ejcn.1600619.

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