Oxford Outcomes, Bethesda, Maryland 20814, USA.
Clin Ther. 2010 Aug;32(8):1448-67. doi: 10.1016/j.clinthera.2010.06.020.
Despite the recommendation from the Centers for Disease Control and Prevention that children between the ages of 6 months and 18 years be vaccinated against influenza annually, vaccination rates remain suboptimal.
This study was conducted to explore factors that influence parents' decisions regarding influenza vaccination for children aged 2 to 12 years, to quantify the relative importance of these factors, to identify an appropriate theoretical model for illustrating the relationships among these factors, and to characterize parents by their likelihood of vaccinating their children against influenza.
A quantitative Web-based survey was administered to a sample of parents from an online panel representative of the US population. Parents were stratified based on self-reported rates of their personal influenza vaccination (every year, sometimes, or never) and the age of their child (2-4 years or 5-12 years). The results were examined by parents' likelihood of vaccinating their child in the next year (high, medium, or low). Participants were asked to rank their agreement with statements representing various beliefs and perceptions about influenza and influenza vaccine on a scale from 1 = strongly agree to 5 = strongly disagree. Parents who indicated that they vaccinate their child every year were asked to select the drivers of their decision to vaccinate; parents who indicated that they never vaccinate their child were asked to select the barriers affecting their decision not to vaccinate; and parents who responded that they sometimes vaccinate their child were asked to select both the drivers and barriers affecting their decision. Participants were then asked to rank the importance of each driver or barrier on a scale from 1 = a little important to 5 = extremely important. Mean agreement ratings were calculated for parents' beliefs and perceptions about influenza and influenza vaccine and were compared across likelihood subgroups. Mean importance ratings of the drivers and barriers to vaccination were also calculated and compared across likelihood subgroups.
The survey sample consisted of 500 parents; their mean (SD) age was 37.4 (6.82) years, 57.2% were female, and 78.2% were non-Hispanic white. Among those who reported that they vaccinated their child against influenza every year or sometimes, the major drivers of vaccination were prevention of influenza (95.1%), a doctor's recommendation (89.5%), and the desire to reduce influenza symptoms (83.3%). Among those who reported sometimes or never vaccinating their child against influenza, barriers to vaccination were more variable. The most common barriers were low perceived risk of influenza (46.0%), the perception that the vaccine caused influenza (44.0%), and side effects caused by the vaccine (36.6%). Distinct differences were found in beliefs and perceptions of influenza and influenza vaccine according to respondents' likelihood of vaccination. A high likelihood of vaccination was associated with a greater perceived threat of influenza and less concern about the efficacy and safety of the vaccine. Convenience was an important factor among parents with a medium likelihood of vaccination. The Health Belief Model was identified as an appropriate theoretical framework for illustrating the factors influencing parents' decision-making about influenza vaccination.
Prevention of influenza, reduction of influenza symptoms, and doctor recommendation were the main drivers of parents' decision to vaccinate their child against influenza. Barriers to vaccination were more variable and primarily included the risk of adverse effects and the perceived low risk of influenza. Increasing parents' awareness of the threat of influenza and the efficacy and safety of the vaccine, as well as improving the convenience of getting vaccinated, may help improve rates of pediatric influenza vaccination.
尽管疾病控制与预防中心建议年龄在 6 个月至 18 岁之间的儿童每年接种流感疫苗,但接种率仍不理想。
本研究旨在探讨影响父母为 2 至 12 岁儿童接种流感疫苗决定的因素,量化这些因素的相对重要性,确定一个合适的理论模型来说明这些因素之间的关系,并描述父母对其子女接种流感疫苗的可能性。
通过在线面板对来自美国人口的样本进行了一项基于网络的定量调查。根据父母自我报告的个人流感疫苗接种率(每年、有时或从不)和子女年龄(2-4 岁或 5-12 岁)对父母进行分层。根据父母在明年为孩子接种疫苗的可能性(高、中、低)来检查结果。参与者被要求对代表对流感和流感疫苗各种信念和看法的陈述进行评分,从 1 = 非常同意到 5 = 非常不同意。表示每年都为孩子接种疫苗的父母被要求选择他们决定接种疫苗的驱动因素;表示从不为孩子接种疫苗的父母被要求选择影响他们不接种疫苗决定的障碍;而表示有时为孩子接种疫苗的父母被要求选择影响他们决定的驱动因素和障碍。然后,参与者被要求对每个驱动因素或障碍的重要性进行评分,从 1 = 有点重要到 5 = 非常重要。计算了父母对流感和流感疫苗的信念和看法的平均同意评分,并根据可能性亚组进行了比较。还计算了接种疫苗的驱动因素和障碍的平均重要性评分,并根据可能性亚组进行了比较。
调查样本由 500 名父母组成;他们的平均(SD)年龄为 37.4(6.82)岁,57.2%为女性,78.2%为非西班牙裔白人。在那些表示每年或有时为孩子接种流感疫苗的人中,接种疫苗的主要驱动因素是预防流感(95.1%)、医生建议(89.5%)和减轻流感症状的愿望(83.3%)。在那些表示有时或从未为孩子接种流感疫苗的人中,接种疫苗的障碍更加多样化。最常见的障碍是流感的低风险感知(46.0%)、疫苗导致流感的感知(44.0%)和疫苗引起的副作用(36.6%)。根据受访者接种疫苗的可能性,对流感和流感疫苗的信念和看法存在明显差异。高接种疫苗的可能性与更大的流感威胁感知和对疫苗功效和安全性的担忧减少有关。便利性是中等接种疫苗可能性的父母的一个重要因素。健康信念模型被确定为说明影响父母对流感疫苗接种决策的因素的合适理论框架。
预防流感、减轻流感症状和医生建议是父母决定为孩子接种流感疫苗的主要驱动因素。接种疫苗的障碍更加多样化,主要包括不良反应的风险和对流感低风险的感知。提高父母对流感威胁和疫苗功效和安全性的认识,以及改善接种疫苗的便利性,可能有助于提高儿童流感疫苗接种率。