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脆弱拟杆菌荚膜多糖生物合成基因座启动子在共生和感染过程中的取向。

Orientations of the Bacteroides fragilis capsular polysaccharide biosynthesis locus promoters during symbiosis and infection.

机构信息

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

出版信息

J Bacteriol. 2010 Nov;192(21):5832-6. doi: 10.1128/JB.00555-10. Epub 2010 Aug 20.

DOI:10.1128/JB.00555-10
PMID:20729352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2953686/
Abstract

Orientations of the seven invertible polysaccharide biosynthesis locus promoters of Bacteroides fragilis were determined from bacteria grown in vitro, from feces of monoassociated and complex colonized mice, and from B. fragilis-induced murine abscesses. Bacteria grown in vivo have greater variability in orientation of polysaccharide locus promoters than culture-grown organisms.

摘要

脆弱拟杆菌 7 个可反转聚糖生物合成基因座启动子的取向，通过体外培养的细菌、单定植和复杂定植的小鼠粪便以及脆弱拟杆菌诱导的鼠脓肿进行了确定。与体外培养的生物体相比，体内生长的细菌在聚糖基因座启动子的取向方面具有更大的可变性。

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J Bacteriol. 2010 Nov;192(21):5832-6. doi: 10.1128/JB.00555-10. Epub 2010 Aug 20.
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本文引用的文献

1
Trans locus inhibitors limit concomitant polysaccharide synthesis in the human gut symbiont Bacteroides fragilis.转座子抑制剂限制了人类肠道共生菌脆弱拟杆菌的多糖同时合成。
Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11976-80. doi: 10.1073/pnas.1005039107. Epub 2010 Jun 14.
2
Role of glycan synthesis in colonization of the mammalian gut by the bacterial symbiont Bacteroides fragilis.聚糖合成在脆弱拟杆菌这一细菌共生体定殖于哺乳动物肠道中的作用。
Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13099-104. doi: 10.1073/pnas.0804220105. Epub 2008 Aug 22.
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Regulation of surface architecture by symbiotic bacteria mediates host colonization.共生细菌对表面结构的调控介导宿主定殖。
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Niche-specific features of the intestinal bacteroidales.肠道拟杆菌目的生态位特异性特征。
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