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Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2413-8. doi: 10.1073/pnas.0608797104. Epub 2007 Feb 6.
2
Bacteroides fragilis synthesizes a DNA invertase affecting both a local and a distant region.脆弱拟杆菌合成一种影响局部和远处区域的DNA转化酶。
J Bacteriol. 2007 Mar;189(5):2119-24. doi: 10.1128/JB.01362-06. Epub 2006 Dec 22.
3
Enhanced biofilm formation and loss of capsule synthesis: deletion of a putative glycosyltransferase in Porphyromonas gingivalis.生物膜形成增强及荚膜合成丧失:牙龈卟啉单胞菌中一个假定糖基转移酶的缺失
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Identification and characterization of the genes encoding a unique surface (S-) layer of Tannerella forsythia.福赛斯坦纳菌独特表面(S-)层编码基因的鉴定与表征
Gene. 2006 Apr 12;371(1):102-11. doi: 10.1016/j.gene.2005.11.027. Epub 2006 Feb 20.
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Identification and characterization of the capsular polysaccharide (K-antigen) locus of Porphyromonas gingivalis.牙龈卟啉单胞菌荚膜多糖(K抗原)基因座的鉴定与表征
Infect Immun. 2006 Jan;74(1):449-60. doi: 10.1128/IAI.74.1.449-460.2006.
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8
Extensive DNA inversions in the B. fragilis genome control variable gene expression.脆弱拟杆菌基因组中的广泛DNA倒位控制可变基因表达。
Science. 2005 Mar 4;307(5714):1463-5. doi: 10.1126/science.1107008.
9
Tyrosine site-specific recombinases mediate DNA inversions affecting the expression of outer surface proteins of Bacteroides fragilis.酪氨酸位点特异性重组酶介导DNA倒位,影响脆弱拟杆菌外表面蛋白的表达。
Mol Microbiol. 2004 Sep;53(5):1319-30. doi: 10.1111/j.1365-2958.2004.04219.x.
10
Human intestinal bacteria as reservoirs for antibiotic resistance genes.作为抗生素抗性基因储存库的人类肠道细菌。
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肠道拟杆菌目的生态位特异性特征。

Niche-specific features of the intestinal bacteroidales.

作者信息

Coyne Michael J, Comstock Laurie E

机构信息

Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA.

出版信息

J Bacteriol. 2008 Jan;190(2):736-42. doi: 10.1128/JB.01559-07. Epub 2007 Nov 9.

DOI:10.1128/JB.01559-07
PMID:17993536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2223690/
Abstract

By analyzing the genomic sequences of 12 Bacteroidales species, we found that all intestinal species have numerous polysaccharide biosynthesis loci, many with promoters that we demonstrate undergo DNA inversion. This feature is not conserved in the Bacteroidales order as a whole, as oral species do not share these genetic features.

摘要

通过分析12种拟杆菌属物种的基因组序列,我们发现所有肠道物种都有大量多糖生物合成基因座,其中许多基因座的启动子会发生DNA倒位。我们证明了这一特征在整个拟杆菌目中并不保守,因为口腔物种不具备这些遗传特征。