Rumberger John A
The Mayo Clinic, Princeton, NJ 08540, USA.
Vasc Health Risk Manag. 2010 Aug 9;6:579-91. doi: 10.2147/vhrm.s7457.
The presence of mural calcification has, for decades, been recognized as a marker for atheromatous plaque in the coronary arteries and the aorta, but only in the past decade has the application of noncontrast computed tomography (CT) been shown to be a reproducible, safe, and convenient test, which now is available worldwide. However, awareness of coronary artery calcium scanning is insufficient and the practitioner must be aware of the available literature as well as understanding clinical recommendations for applications and interpretation. It is best applied in the medium/intermediate risk, asymptomatic adult regardless of ethnicity across broad age ranges for both men and women; additional prognostic information is also afforded from the calcium distribution in the coronary artery system. Additionally, information can also be derived from the same CT scan regarding heart and aorta size and assessment of the epicardial fat pad (an anatomic marker for the metabolic syndrome). Details of how this test can aid in cardiovascular risk assessment and management in adults are provided.
几十年来,壁层钙化的存在一直被视为冠状动脉和主动脉粥样斑块的一个标志,但直到过去十年,非增强计算机断层扫描(CT)的应用才被证明是一种可重复、安全且便捷的检查方法,目前在全球范围内均可使用。然而,对冠状动脉钙化扫描的认识还不够充分,从业者必须了解现有文献,并理解关于其应用和解读的临床建议。它最适用于中/中度风险、无症状的成年人,无论种族如何,涵盖广泛的年龄范围,包括男性和女性;冠状动脉系统中的钙分布也能提供额外的预后信息。此外,从同一CT扫描中还可以获得有关心脏和主动脉大小以及心外膜脂肪垫评估(代谢综合征的一个解剖学标志)的信息。本文提供了该检查如何有助于成人心血管风险评估和管理的详细信息。