Laboratory of Epidemiology and Biometry, National Institute on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, MSC 9304, Bethesda, Maryland 20892-9304, USA.
J Stud Alcohol Drugs. 2010 Sep;71(5):751-60. doi: 10.15288/jsad.2010.71.751.
The objective of this study was to test the ability of a question on frequency of drinking 5+ (for men) or 4+ (for women) drinks to screen for drug use and drug-use disorders (DUDs) in a general population sample.
Using data collected in 2001-2002 from a representative U.S. adult population sample (N= 43,093), including a subsample of those with past-year emergency-department use (n = 8,525), past-year frequency of drinking 5+/4+ drinks was evaluated as a screener for drug use and DUDs for four categories of illicit drugs.
Sensitivities and specificities of the 5+/4+ drinks screener were 72.4% and 76.6% for any drug dependence, 71.9% and 77.3% for any DUD, and 63.3% and 78.9% for any drug use in the general population. Sensitivities and specificities were higher for marijuana and cocaine/crack and lowest for illicit prescription drugs. Optimal screening cut-points were once a month or more for cocaine/crack dependence, either once or more a month or seven or more times a year for cocaine/crack DUDs, seven or more times a year for cocaine/crack use, and once or more a year for the other drug use and DUD measures. Sensitivity and specificity were similar among adults who had visited an emergency department in the past year, and the optimal screening cutpoints were identical.
Past-year frequency of drinking 5+/4+ drinks was quite accurate as a screener for past-year marijuana and cocaine/crack use and DUDs, but it was less accurate for illicit prescription drug use and DUDs. Its drug-screening potential can be thought of as "added value" from an item already likely to be asked in the interest of detecting problem drinking. Future work may consider using the alcohol consumption screener as a starting point, with follow-up questions to assess illicit drug use among those who screen positive.
本研究旨在检验一个问题(男性饮酒 5 杯以上或女性饮酒 4 杯以上的频率)筛查一般人群中药物使用和药物使用障碍(DUD)的能力。
使用 2001-2002 年从美国成人代表性人群样本(N=43093)中收集的数据,包括过去一年急诊就诊的亚样本(n=8525),评估过去一年 5+/4+杯饮酒频率作为筛查四种非法药物使用和 DUD 的指标。
5+/4+杯饮酒筛查对任何药物依赖的灵敏度和特异性分别为 72.4%和 76.6%,对任何 DUD 的灵敏度和特异性分别为 71.9%和 77.3%,对一般人群中任何药物使用的灵敏度和特异性分别为 63.3%和 78.9%。大麻和可卡因/快克的灵敏度和特异性较高,非法处方药物的灵敏度和特异性较低。可卡因/快克依赖的最佳筛查切点为每月一次或以上,可卡因/快克 DUD 的最佳筛查切点为每月一次或以上或每年七次或以上,可卡因/快克使用的最佳筛查切点为每年七次或以上,其他药物使用和 DUD 测量的最佳筛查切点为每年一次或以上。过去一年曾就诊于急诊的成年人的敏感性和特异性相似,最佳筛查切点也相同。
过去一年饮酒 5+/4+杯的频率作为过去一年大麻和可卡因/快克使用和 DUD 的筛查指标相当准确,但对非法处方药物使用和 DUD 的准确性较低。它的药物筛查潜力可以被认为是从已经可能被问到的检测问题饮酒的项目中“附加的价值”。未来的研究可以考虑使用酒精消费筛查器作为起点,对筛查阳性者进行非法药物使用评估。