仍然纠缠不清：中心纺锤体的组装由多种微管调节剂共同调控。
Still entangled: assembly of the central spindle by multiple microtubule modulators.
机构信息
The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.
出版信息
Semin Cell Dev Biol. 2010 Dec;21(9):899-908. doi: 10.1016/j.semcdb.2010.08.005. Epub 2010 Aug 21.
The central spindle is a microtubule-based structure that assembles during anaphase of mitosis in animal cells and is essential for multiple steps of cytokinesis. Central spindle assembly occurs by the cooperative action of multiple microtubule motors and modulators. Here, we review the mechanism by which the central spindle is formed, the role of several key proteins in this process and how central spindle assembly is temporally and spatially coordinated with mitosis.
中心纺锤体是一种基于微管的结构，在动物细胞的有丝分裂后期组装，对胞质分裂的多个步骤至关重要。中心纺锤体的组装是通过多种微管马达和调节剂的协同作用实现的。在这里，我们回顾了中心纺锤体形成的机制，这个过程中的几个关键蛋白的作用，以及中心纺锤体的组装如何与有丝分裂在时间和空间上协调。
Zotero 插件