From the Boston University School of Medicine; the Planned Parenthood League of Massachusetts; and Brigham and Women's Hospital, Boston, Massachusetts.
Obstet Gynecol. 2010 Sep;116(3):633-640. doi: 10.1097/AOG.0b013e3181eb6b0f.
To estimate whether women receiving daily text-message reminders have increased oral contraceptive pill adherence compared with women not receiving reminders.
This randomized controlled trial estimated whether there was an effect of daily text-message reminders on oral contraceptive pill adherence of new oral contraceptive pill users. Pill-taking was tracked for 3 months by an electronic monitoring device with wireless data collection. During the study period, participants assigned the intervention received a daily reminder text message. Eighty-two women were assigned randomly to detect a 1.6+/-2.0 pill difference (90% power, 5% alpha, 15% dropout).
Participants were 79% white, non-Hispanic, 99% high school graduates, and 99% nulliparous with a mean age of 22 years. Most reported condom use with past coital activity, and more than half reported prior emergency contraception use. The mean number of missed pills per cycle did not differ significantly between the groups: 4.9+/-3.0 for the text-message group and 4.6+/-3.5 for the control group (P=.60). The number of missed pills per cycle increased over the course of the study, but this pattern did not increase differentially between the groups. Adherence recorded by the electronic monitoring device indicated much poorer adherence than that recorded by patient diaries. Despite poor pill-taking, there were no pregnancies.
Daily text-message reminders did not improve oral contraceptive pill adherence. Although the lack of benefit may be attributed to the frequent use of alternative reminder systems in the control group, the rate of missed pills when measured objectively was still very high in both groups.
Clinicaltrials.gov, www.clinicaltrials.gov, NCT00733707.
I.
评估每日接受短信提醒的女性与未接受提醒的女性相比，其口服避孕药的依从性是否有所提高。
本随机对照试验评估了每日短信提醒对新口服避孕药使用者口服避孕药依从性的影响。通过具有无线数据采集功能的电子监测设备，在 3 个月的研究期间跟踪服药情况。在研究期间，接受干预措施的参与者每天都会收到一条提醒短信。82 名女性被随机分配，以检测 1.6+/-2.0 粒药物差异（90%效力，5%alpha，15%失访）。
参与者 99%为白人，非西班牙裔，99%为高中毕业生，且 99%为未育，平均年龄为 22 岁。大多数人报告过去性行为时使用了避孕套，超过一半的人报告曾使用过紧急避孕药。两组每个周期漏服的药片数无显著差异：短信组为 4.9+/-3.0 片，对照组为 4.6+/-3.5 片（P=.60）。随着研究的进行，每个周期漏服的药片数有所增加，但两组之间的这种模式没有明显差异。电子监测设备记录的依从性明显低于患者日记记录的依从性。尽管服药情况不佳，但两组均未发生妊娠。
每日短信提醒并未提高口服避孕药的依从性。尽管缺乏益处可能归因于对照组频繁使用替代提醒系统，但两组实际漏服的药物数量仍然非常高。
Clinicaltrials.gov，www.clinicaltrials.gov，NCT00733707。
I。
