Institute of Materials Research and Engineering, 3 Research Link, Singapore 117602.
Microsc Res Tech. 2011 Jul;74(7):563-76. doi: 10.1002/jemt.20912. Epub 2010 Aug 23.
Fluorescent optical probes have been intensively used in the area of bio-imaging. In this review article, we describe the recent advancements in the synthesis and application of bimodal magnetic-fluorescent probes for bioimaging. The bimodal probes consist of fluorescent [semiconducting quantum dots (e.g., CdSe/ZnS) or rare-earth doped (e.g., NaYF(4) :Yb,Er)] nanoparticles (NPs) and magnetic (iron oxide or gadolinium based) NPs for optical and magnetic resonance (MR) imaging.
荧光光学探针在生物成像领域得到了广泛的应用。在这篇综述文章中,我们描述了用于生物成像的双模磁性荧光探针的合成和应用的最新进展。双模探针由荧光(半导体量子点(例如 CdSe/ZnS)或稀土掺杂(例如 NaYF(4) :Yb,Er))纳米粒子(NPs)和磁性(氧化铁或钆基)NPs 组成,用于光学和磁共振(MR)成像。