Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario K1N 6N5, Canada.
Org Lett. 2010 Sep 17;12(18):4126-9. doi: 10.1021/ol101714p.
Palladium-catalyzed double carbonylation of o-dihaloarenes with amines in phosphonium salt ionic liquids proceeds efficiently to give the corresponding N-substituted phthalimides. This process can tolerate a wide array of functional groups and affords products in excellent yields. The recyclability of the catalytic system was also investigated.
钯催化的邻二卤代芳烃与胺在鏻盐离子液体中的双羰基化反应高效进行，得到相应的 N-取代邻苯二甲酰亚胺。该过程可以容忍广泛的官能团，并以优异的收率得到产物。还研究了催化体系的可回收性。
