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定义间充质基质细胞治疗的风险。

Defining the risks of mesenchymal stromal cell therapy.

机构信息

Texas A&M Health Science College of Medicine, Institute for Regenerative Medicine at Scott & White, Temple, TX 76502, USA.

出版信息

Cytotherapy. 2010 Sep;12(5):576-8. doi: 10.3109/14653249.2010.507330.

DOI:10.3109/14653249.2010.507330
PMID:20735162
Abstract

Abstract We address the issue of the potential for malignant transformation of cultured mesenchymal stromal cells (MSC) commonly used in clinical cell-therapy protocols and describe the culture conditions under which tumorigenesis is likely to be an extremely uncommon event.

摘要

摘要 我们探讨了临床细胞治疗方案中常用的培养间充质基质细胞（MSC）发生恶性转化的可能性，并描述了可能极不可能发生致瘤的培养条件。

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