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NCDR ACTION 注册-GWTG:改变当代急性心肌梗死的临床护理。

The NCDR ACTION Registry-GWTG: transforming contemporary acute myocardial infarction clinical care.

机构信息

Duke Clinical Research Institute, 2400 Pratt Street, Durham, NC 27705, USA.

出版信息

Heart. 2010 Nov;96(22):1798-802. doi: 10.1136/hrt.2010.200261. Epub 2010 Aug 23.

DOI:10.1136/hrt.2010.200261
PMID:20736202
Abstract

AIMS

The NCDR ACTION Registry-GWTG collects detailed in-hospital clinical, process-of-care and outcomes data for patients admitted with acute myocardial infarction (AMI) in the USA. The registry is a national AMI surveillance system that contributes to the scientific enquiry process of AMI care through the facilitation of local and national quality improvement efforts.

INTERVENTIONS

No treatments are mandated, participating centres receive routine quality-of-care and outcomes performance feedback reports and access to quality of care tools, such as dosing algorithms and standing orders.

POPULATION

AMI patients are retrospectively identified. No informed consent is required, as data are anonymised. From January 2007 to date, 147 165 records have been submitted from 383 participating US hospitals. Patients with a primary diagnosis of ST-segment elevation myocardial infarction or non-ST-segment elevation myocardial infarction are eligible for enrolment in the registry. These patients must have ischemic symptoms and electrocardiogram changes, and/or positive cardiac markers within 24 hours of initial presentation.

BASELINE DATA

Approximately 350 fields encompassing patient demographics, medical history and risk factors, hospital presentation, initial cardiac status, medications and associated doses, reperfusion strategy, procedures, laboratory values, and outcomes. Data are manually entered by study personnel; there are non-financial incentives at the hospital level. Completeness within the registry is noteworthy with most fields at less than 5% missing.

ENDPOINTS

Main outcome measures include American College of Cardiology/American Heart Association myocardial infarction performance indicators, as well as in-hospital patient outcomes. Data are available for research by application to: http://www.ncdr.com.

摘要

目的

NCDR ACTION 注册-GWTG 收集美国因急性心肌梗死(AMI)住院患者的详细院内临床、治疗过程和结局数据。该注册是一个全国性的 AMI 监测系统,通过促进当地和全国的质量改进努力,为 AMI 护理的科学研究过程做出贡献。

干预措施

不强制要求治疗,参与中心会收到常规的质量和结果绩效反馈报告,并可以使用质量工具,如剂量算法和标准医嘱。

人群

AMI 患者被回顾性识别。不需要知情同意,因为数据是匿名的。自 2007 年 1 月至今,已有 383 家美国医院提交了 147165 份记录。符合该注册条件的患者是患有 ST 段抬高型心肌梗死或非 ST 段抬高型心肌梗死的主要诊断的患者。这些患者必须在初始表现的 24 小时内出现缺血症状和心电图改变和/或阳性心脏标志物。

基线数据

大约有 350 个字段涵盖了患者的人口统计学特征、病史和危险因素、入院情况、初始心脏状态、药物和相关剂量、再灌注策略、程序、实验室值和结局。数据由研究人员手动输入;医院层面有非财务激励措施。该注册的完整性值得注意,大多数字段的缺失率小于 5%。

结局

主要结局指标包括美国心脏病学院/美国心脏协会心肌梗死表现指标,以及住院患者结局。有研究需求者可通过向以下网址申请获取数据:http://www.ncdr.com。

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