Department of Pathology and Laboratory Medicine, Vancouver, BC, Canada.
Pediatr Infect Dis J. 2011 Feb;30(2):176-8. doi: 10.1097/INF.0b013e3181f41b2e.
Genital ulceration is a rare manifestation of infectious mononucleosis caused by Epstein-Barr virus (EBV). We report a girl with severe genital ulceration and tissue necrosis during primary EBV infection that required surgical debridement. The excised genital tissue was EBV polymerase chain reaction-positive whereas in situ hybridization was negative. This suggests that the ulceration was likely because of the inflammatory response to the virus and not because of the intense viral infection of the genitalia.
生殖器溃疡是由 Epstein-Barr 病毒（EBV）引起的传染性单核细胞增多症的罕见表现。我们报告了一例在原发性 EBV 感染期间出现严重生殖器溃疡和组织坏死的女孩，需要手术清创。切除的生殖器组织 EBV 聚合酶链反应阳性，原位杂交阴性。这表明溃疡可能是由于对病毒的炎症反应，而不是由于生殖器的强烈病毒感染。
