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[胃神经源性营养不良中核酸和环磷酸腺苷浓度的变化]

[Change in the concentration of nucleic acids and cAMP in neurogenic dystrophies of the stomach].

作者信息

Zavodskaia I S, Migas E A

出版信息

Biull Eksp Biol Med. 1978 Apr;85(4):405-7.

PMID:207370
Abstract

There proved to be a reduction of the RNA content in the tissue of the rat stomach in its dystrophic affection induced by traumatization of the duodenum, this pointing to the reconstruction of the cell genetic apparatus under conditions of extreme stimulation. Under the same experimental conditions there was a pronounced decrease of the cAMP level in the gastric mucosa of rabbits. The significance of the changes in the mechanism of the development of destructive and metabolic disturbances in the neurogenic dystrophic affections induced by extreme stimulation is discussed.

摘要

事实证明,在十二指肠创伤诱发大鼠胃组织营养不良性病变时,其RNA含量会降低,这表明在极端刺激条件下细胞遗传装置的重建。在相同实验条件下,家兔胃黏膜中的cAMP水平显著下降。文中讨论了极端刺激诱发的神经源性营养不良性病变中,破坏性和代谢紊乱发生机制变化的意义。

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