Department of Psychiatry, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kota Bharu, Malaysia.
Qual Life Res. 2011 Feb;20(1):91-100. doi: 10.1007/s11136-010-9729-y. Epub 2010 Aug 26.
The aim of this study was to determine the socio-demographic, clinical and psychological factors influencing the quality of life (QOL) in patients with human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS).
This was a cross-sectional study on 271 patients with HIV infection attending an HIV clinic in Kota Bharu, Malaysia. Participants completed the Malay version of the Functional Assessment of HIV Infection (FAHI) and Malay Hospital Anxiety Depression Scale (HADS).
The patients functioned satisfactorily in the physical domain. They were mostly impaired in the social domain. Those who acquired the HIV infection via a heterosexual route seemed to have a significantly lower social well-being, while those who acquired HIV via drug injection were not associated with losses in the overall QOL or any of its domains. Non-disclosure paradoxically had a greater effect on social well-being. About 38% had possible anxiety, depression or both, and these emotional disturbances were significantly associated with total FAHI and its five domains.
Psychological and social well-beings were more affected than physical well-being in out-patients with HIV infection in Kota Bharu, Malaysia. The study suggests that the patients with HIV infection should receive better psycho-education and psychological intervention.
本研究旨在确定影响人类免疫缺陷病毒感染和获得性免疫缺陷综合征（HIV/AIDS）患者生活质量（QOL）的社会人口学、临床和心理因素。
这是一项在马来西亚哥打巴鲁的一家 HIV 诊所就诊的 271 名 HIV 感染者的横断面研究。参与者完成了马来语版的 HIV 感染功能评估（FAHI）和马来语医院焦虑抑郁量表（HADS）。
患者在身体领域功能表现良好。他们在社会领域大多受到损害。那些通过异性恋途径感染 HIV 的人社会幸福感明显较低，而那些通过注射毒品感染 HIV 的人则与整体 QOL 或其任何领域的损失无关。隐瞒身份反而对社会幸福感有更大的影响。约 38%的人可能有焦虑、抑郁或两者兼有，这些情绪障碍与总 FAHI 及其五个领域显著相关。
在马来西亚哥打巴鲁的门诊 HIV 感染者中，心理和社会幸福感比身体幸福感受到的影响更大。研究表明，HIV 感染者应接受更好的心理教育和心理干预。
