Vasylyev Marta, Davtyan Hayk, Denisiuk Olga, Chadwick Jayaraj Joshua, Koval Tetyana, Piddubna Anna, Sluzhynska Maryana, Sluzhynska Oleksandra, Mulcahy Fiona
Lviv Regional Public Health Center, Charitable Salus Foundation, Lviv, Ukraine.
TB Research and Prevention Center, Yerevan, Armenia.
J Infect Dev Ctries. 2019 Jul 31;13(7.1):111S-117S. doi: 10.3855/jidc.11295.
People who inject drugs (PWID) are one of the key populations most vulnerable to HIV infection, with 28 times higher prevalence compared to the rest of the population. PWID are known to have many physical, psychological and lifestyle challenges that can influence access to care. Depression is common among PWID living with HIV. It has major effect on health-related quality of life (HRQoL) and is influencing adherence to antiretroviral therapy. This study was conducted to explore how anxiety and depression affect HRQoL among HIV-positive PWID in Ukraine. It will provide knowledge for the further policy development.
A descriptive cross-sectional study using data from interviewer- administrated questionnaires was performed. The questionnaire was based on the Hospital Anxiety and Depression Scale. The questionnaire on HRQoL was based on the SF-36.
Among the 90 HIV positive PWID 74% (67) and 61% (55) had anxiety and depression scores higher than 7 respectively, indicating that most patients had mental health problems. Average scores for general health (40), role limitations due to physical (44) and emotional health (34), vitality (41) and mental health (45) had mean scores less than 50 along with total physical (43) and mental health scores (35). Having an HIV positive partner or partner with unknown HIV status increases anxiety in HIV positive PWID.
There are increased depressive and anxiety symptoms and poorer QoL among HIV-positive PWID in Ukraine. Strategies focusing on psychosocial support addressing QoL as part of HIV care could improve health outcomes for these comorbid and debilitating conditions.
注射毒品者（PWID）是最易感染艾滋病毒的关键人群之一，其感染率比其他人群高28倍。众所周知，注射毒品者面临许多身体、心理和生活方式方面的挑战，这些挑战可能会影响他们获得医疗服务的机会。抑郁症在感染艾滋病毒的注射毒品者中很常见。它对健康相关生活质量（HRQoL）有重大影响，并影响对抗逆转录病毒疗法的依从性。本研究旨在探讨焦虑和抑郁如何影响乌克兰艾滋病毒呈阳性的注射毒品者的健康相关生活质量。它将为进一步的政策制定提供知识。
采用描述性横断面研究，使用访谈员管理的问卷数据。问卷基于医院焦虑和抑郁量表。关于健康相关生活质量的问卷基于SF-36。
在90名艾滋病毒呈阳性的注射毒品者中，74%（67人）和61%（55人）的焦虑和抑郁得分分别高于7分，这表明大多数患者存在心理健康问题。总体健康（40分）、身体（44分）和情绪健康（34分）导致的角色限制、活力（41分）和心理健康（45分）的平均得分低于50分，同时身体（43分）和心理健康总分（35分）也较低。有艾滋病毒呈阳性的伴侣或艾滋病毒状况不明的伴侣会增加艾滋病毒呈阳性的注射毒品者中的焦虑情绪。
乌克兰艾滋病毒呈阳性的注射毒品者中抑郁和焦虑症状增加，生活质量较差。将关注心理社会支持以改善生活质量作为艾滋病毒护理一部分的策略，可改善这些共病和使人衰弱状况的健康结果。
